Scientist, Pharmacokinetics (Onsite)
About The Position
The Department of Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) is seeking a motivated bioanalytical scientist to support drug discovery and early pre-clinical development. The Scientist executes and troubleshoots quantitative bioanalytical methods for small molecules, peptides, and biologics using LC-MS and ligand binding assay (LBA) platforms, delivering high-quality data to advance the pipeline. The role involves developing, validating, and executing bioanalytical methods; generating data for pharmacokinetic, pharmacodynamic, and in vitro studies; preparing biological-matrix samples manually and with automated systems; maintaining laboratory equipment and compliance; and supporting high-throughput workflows through operation and troubleshooting of robotics and automated systems. The position is onsite in West Point, Pennsylvania. The role includes 10% travel and domestic relocation is listed.
Requirements
- Bachelor’s degree with at least 3 years of relevant laboratory experience, or a master’s degree with 1–2 years of relevant experience, in analytical chemistry, pharmaceutical sciences, pharmacology, biomedical sciences, chemical engineering, or a related field.
- Experience quantitating large molecules or biologics using ligand binding assays.
- Ability to collaborate effectively within multidisciplinary scientific teams.
- Excellent written and verbal communication skills, including the ability to present scientific data clearly.
- Proficiency with Microsoft Office Suite, including Excel, Word, and PowerPoint, and standard laboratory software.
Nice To Haves
- Basic understanding of statistical analysis and pharmacokinetic principles.
- Experience with liquid chromatography and mass spectrometry for quantitative analysis of small molecules and/or peptides in biological matrices.
Responsibilities
- Develop, validate, execute, and troubleshoot quantitative bioanalytical methods using LC-MS/MS, ligand binding assays, and/or hybrid LC-MS/LBA workflows.
- Generate, analyze, and deliver high-quality bioanalytical data for pharmacokinetic, pharmacodynamic, and in vitro studies of small- and large-molecule therapeutics within established timelines.
- Perform manual and automated sample preparation, including protein precipitation, solid-phase extraction, and immunocapture or affinity purification for biological matrices.
- Maintain laboratory equipment and ensure laboratory operations comply with safety requirements, internal SOPs, and regulatory guidelines.
- Support high-throughput workflows by operating and troubleshooting robotics and automated systems.
Benefits
- Medical, dental, vision, and other insurance benefits for employees and family.
- Retirement benefits, including a 401(k).
- Paid holidays, vacation, compassionate days, and sick days.
- Eligible for an annual bonus and long-term incentive, if applicable.
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
