TEMP - Scientist, Medicinal Chemistry

Neurocrine Biosciences • San Diego, CA

21h

About The Position

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. They are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis and uterine fibroids, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across their core therapeutic areas. This role is responsible for the design, synthesis, purification, and characterization of intermediates and bioactive compounds through the use of techniques such as column chromatography (e.g., high performance liquid chromatography, automated normal phase purification), nuclear magnetic resonance and parallel or combinatorial synthesis. The Scientist prepares technical reports, summaries, protocols, and quantitative analyses, and is responsible for the communication and presentation of results to the project team to facilitate effective decision making.

Requirements

• BS/BA degree with significant relevant experience
• Recognizes fundamental anomalies in data points and identifies issues in experiments / processes
• Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals
• Strong knowledge of scientific discipline
• Good knowledge of scientific principles, methods and techniques
• Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools
• Strong computer skills
• Good problem-solving, analytical thinking skills
• Detail oriented
• Ability to meet deadlines
• Excellent communication skills with the ability to collaborate with cross-functional scientists

Nice To Haves

• PhD in Synthetic Organic Chemistry or related field preferred
• Working knowledge of any or all of the following: organic synthesis, parallel synthesis, medicinal chemistry, lab automation, and purification in the optimization of lead compounds is preferred
• MS/MA degree in Synthetic Organic Chemistry preferred and some similar experience noted above

Responsibilities

• Plays key role in the rapid optimization of lead molecules utilizing modern technology available to medicinal chemists such as automated synthesis and purification
• Participates in a multidisciplinary team committed to the continuous improvement of the lead optimization process as well as the expeditious identification of development compounds
• Designs, plans and conducts synthesis of intermediates and analog libraries as well communicates results to the project or program team
• Other duties as assigned

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree