Scientist - Medicinal Chemistry

Amgen • Thousand Oaks, CA

11h • Onsite

About The Position

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Scientist – Medicinal Chemistry What you will do Let’s do this. Let’s change the world. In this vital role you be part of an innovative Medicinal Chemistry group with responsibilities including (but not limited to) the design, synthesis, and purification of novel compounds for potential clinical drug development. This will also include the opportunity to work within Amgen’s Induced Proximity Platform (IPP), which is focused on novel and innovative approaches to modulate intractable targets in diseases using the emerging PROTAC modality. This is an onsite laboratory position at our Thousand Oaks, CA site.

Requirements

• Doctorate Degree
• Master’s degree and 2 years of laboratory experience OR Bachelor’s degree and 4 years of laboratory experience

Nice To Haves

• Track record of accomplishments (e.g., peer-reviewed publications)
• Demonstrated ability to scout and troubleshoot synthetic routes, and perform high difficulty synthetic chemistry
• Clear understanding of structural determination using NMR and Mass Spectral techniques as well as knowledge of purification methods
• Demonstration of good lab practices, with particular attention to safety
• Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams

Responsibilities

• The Scientist will work in teams to develop, implement and perform organic reactions for ongoing Medicinal Chemistry teams, including troubleshooting of synthetic routes and reactions, scouting of new synthetic routes and performing high difficulty synthetic chemistry.
• Contribute to the design of new compounds and the development of structure-activity relationships.
• Perform structural determinations using NMR and mass spectral techniques and purify compounds using a variety of techniques.
• Be recognized as a lab leader and should demonstrate excellent verbal and written communication skills.
• Maintaining laboratory notebooks, participating in group and project meetings and, as needed, presenting to groups and aiding in the writing of papers and patent applications.

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees