Scientist, In Vivo Cancer Modeling
About The Position
Cloverleaf Bio is an early-stage therapeutics company that is developing a new class of engineered RNA therapeutics. We are seeking an experienced in vivo Scientist to join our team. In this position, you will work in close conjunction with our founding team in the creation and development of a completely novel family of RNA therapeutics. Your responsibilities will include designing and executing in house animal experiments in mice, proposing, planning and coordinating toxicity, pharmacology and efficacy studies at CROs, performing in vitro experiments to characterize the mechanism and potency of candidate RNAs, and providing in vivo pharmacology and physiology expertise to accelerate development of our tRNA therapeutics.
Requirements
- PhD in Cancer Biology, Molecular Biology, or related fields
- Hands-on experience with mouse models of disease (preferably oncology)
- Hands-on experience with tissue collection and processing
- Hands-on experience with routine drug administration including intravenous and subcutaneous injections
- Demonstrated ability to independently plan and execute in-vivo studies
- Demonstrated ability in data analysis and interpretation
- Skilled in mammalian cell culture
- Skilled in molecular biology techniques
Nice To Haves
- Strong molecular/cell biology experience, particularly in immunology, RNA biochemistry and/or protein biochemistry
- Hands-on experience with flow cytometry
- Hands-on experience with IHC
- Hands-on experience with ELISA
- Experience with design/development RNA therapeutics
- Experience with lipid nanoparticles
- Previous experience selecting and overseeing work at CROs
Responsibilities
- Designing and executing in house animal experiments in mice
- Proposing, planning and coordinating toxicity, pharmacology and efficacy studies at CROs
- Performing in vitro experiments to characterize the mechanism and potency of candidate RNAs
- Providing in vivo pharmacology and physiology expertise to accelerate development of our tRNA therapeutics
Benefits
- Competitive salary commensurate with experience
- Strong equity incentives
- Medical, dental, and vision coverage
- 401k retirement including employer match
- A stimulating, collegial, and fast-paced environment
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
