Scientist III, Biological Science
About The Position
We are seeking a motivated Scientist III to join our drug discovery team and help advance innovative small molecule programs through high-quality assay development, screening, and automation-enabled workflows. In this role, you will independently design, execute, optimize, and interpret biochemical and cell-based assays, including high-throughput screening assays in 384- and 1536-well formats. You will partner closely with biologists, biochemists, medicinal chemists, and automation teams to generate decision-making data, troubleshoot complex workflows, and apply new technologies that improve assay performance and accelerate the Design, Make, Test, Analyze (DMTA) cycle. This is an exciting opportunity for a hands-on scientist who enjoys building robust assays, applying enzyme kinetics expertise, and leveraging lab automation platforms such as the Agilent BRAVO, Beckman ECHO, Formulatrix Mantis, and Certus Flex to support fast-paced discovery research.
Requirements
- Bachelor’s or Master’s degree in biological sciences, biochemistry, pharmacology, or a related scientific discipline.
- Minimum of 5+ years of relevant laboratory experience with a bachelor’s degree or 3+ years with a master’s degree, preferably in the biotech or pharmaceutical industry.
- Demonstrated experience developing and optimizing biochemical, cell-free, or cell-based assays for drug discovery applications.
- Hands-on experience with high-throughput screening formats, particularly 384- or 1536-well assay platforms.
- Strong understanding of enzyme kinetics and the ability to apply kinetic principles to assay design and data interpretation.
- Experience operating or programming liquid handlers and automation platforms such as Agilent BRAVO, Beckman ECHO, Formulatrix Mantis, Certus Flex, or similar systems.
- Strong data analysis, documentation, communication, and problem-solving skills.
- Ability to manage multiple priorities in a fast-paced, collaborative research environment.
Nice To Haves
- Experience managing, transferring, or analyzing studies conducted with CRO partners.
- Interest in emerging lab automation technologies, instrumentation, and assay miniaturization strategies.
- Ability to clearly communicate scientific concepts, experimental results, and recommendations in both written and verbal formats.
Responsibilities
- Develop, optimize, and execute high-throughput screening assays in 384- and 1536-well formats, including both cell-free and cell-based assay systems.
- Apply knowledge of enzyme kinetics to design experiments, interpret assay performance, and support mechanism-of-action studies for small molecules.
- Operate, program, and troubleshoot liquid handling and automation platforms, including systems such as Agilent BRAVO, Beckman ECHO, Formulatrix Mantis, and Certus Flex.
- Evaluate and implement lab automation technologies that improve assay workflows, increase throughput, and reduce DMTA cycle time.
- Maintain and calibrate laboratory equipment to support experimental precision, reproducibility, and operational excellence.
- Manage CRO studies and external collaborations as needed to support project deliverables.
- Follow all safety, quality control, and documentation procedures.
- Analyze experimental results, assess assay quality, and summarize key findings to inform program decisions.
- Document experiments, protocols, and data clearly in electronic notebooks, LIMS, and other required systems.
- Prepare reports, presentations, and data summaries for internal teams and cross-functional stakeholders.
- Work in a collaborative, cross-functional environment to solve scientific and technical challenges.
- Mentor and train colleagues on assay development, automation workflows, and best practices.
- Contribute to a team culture focused on scientific rigor, innovation, and continuous improvement.
- Perform other duties and responsibilities as assigned.
Benefits
- Competitive salary and annual bonus.
- Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
- Generous parental leave and family planning benefits.
- Outstanding culture and opportunities for personal and professional growth.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Associate degree
