Scientist II/Senior Scientist, Cell and Molecular Biology

Magnet Biomedicine • Boston, MA

4h • $130,000 - $170,000

About The Position

Magnet Biomedicine is seeking a highly motivated, hands-on biologist to design, execute, and interpret experiments that develop protein-protein interaction strategies for modulating target protein function. The role contributes to the discovery and development of molecular glue therapeutics, including next-generation treatments for oncology, immunology, and inflammation.

The successful candidate will conduct phenotypic cell-based assays, enzymatic assays, and binding experiments, and collaborate with a multidisciplinary team. The position calls for scientific curiosity, collaboration, and the ability to expand technical expertise in a fast-paced research environment.

Requirements

• PhD in Cell Biology, Molecular Biology, Biochemistry, Genetics, or a related discipline with 2–8 years of biotech experience; or a BS/MS with 8+ years of industry experience, including biotech.
• Hands-on experience with small-molecule binding and inhibition assays.
• Strong experimental design, execution, and analytical skills.
• Strong analytical mindset and familiarity with relevant statistical methods.
• Experience working with human whole blood, human biopsies, and/or lentivirus (BCL2+).
• Scientific productivity demonstrated through publications, presentations, or equivalent accomplishments.
• Proficiency with scientific data analysis and visualization software.
• Intellectual curiosity, scientific rigor, and a positive, collegial attitude.
• Willingness to learn new techniques and rapidly develop expertise in emerging technologies.

Nice To Haves

• Hands-on work with molecular glue therapeutics or targeted protein degradation approaches.
• Strong working knowledge of immunology or oncology.
• Experience using confocal and fluorescence microscopy methodologies in drug discovery.
• Experience leveraging flow cytometry and cell-based screening platforms to support research and discovery efforts.
• Demonstrated ability to oversee and collaborate with external CROs to achieve project objectives and timelines.

Responsibilities

• Design and execute cellular and molecular biology experiments to support discovery programs.
• Evaluate protein-protein interactions using approaches such as NanoBiT, NanoBRET, IP-MS, ALPHAscreen, and related technologies.
• Experiment with human whole blood, human biopsies, and/or lentivirus (BCL2+).
• Analyze experimental data, draw scientific conclusions, and communicate results to project teams and company colleagues.
• Maintain accurate and complete experimental records in the electronic laboratory notebook (ELN).
• Independently troubleshoot technical experimental challenges and seek input when appropriate.
• Collaborate with scientists across disciplines to solve scientific problems and advance research objectives.
• Expand technical expertise and adopt new methodologies to support evolving research needs.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level