Scientist II, Antisense/siRNA and Peptide Purification
About The Position
At Biogen, we are advancing science to transform patients’ lives. We are seeking a highly motivated Scientist II to join our Technical Development team in Cambridge, MA, focused on oligonucleotide (Antisense/siRNA) and Peptide Purification. This is an exciting opportunity to design and develop robust, scalable purification processes that directly impact clinical and commercial therapeutics. You will play a key role in advancing next-generation modalities by bridging early development with manufacturing, working in a highly collaborative, cross-functional environment. Your work will contribute to building state-of-the-art platform processes that improve product quality, scalability, and efficiently enabling delivery of innovative therapies to patients. We are a team of chemists and chemical engineers engaged in the design of innovative processes which supply new medicines to patients. We focus on developing safe, economical, sustainable, cost-effective, and robust processes to support clinical trials and the launch of new medicines across various drug modalities. We are driven by first principles science, data-driven decision-making, and collaborative teamwork.
Requirements
- Ph.D. degree in chemical engineering, chemistry, or a related science with 0-3 years of experience
- Master’s degree in chemical engineering, chemistry, or a related science with 4+ years of experience in pharmaceutical or biotech settings.
- Bachelor’s degree in chemical engineering, chemistry, or a related science with 6+ years of relevant experience in pharmaceutical or biotech settings.
- Experience in purification process development, preferably in an industrial environment.
- Strong analytical skills and statistical analysis expertise.
- Proficiency in technical writing and presenting technical data.
Nice To Haves
- Experience in developing processes for oligonucleotides, peptides, and/or proteins.
- Familiarity with GMP manufacturing processes.
- Collaborative mindset with experience working in cross-functional teams.
Responsibilities
- Design, develop, and scale purification processes across development stages (early development through commercial)
- Apply data-driven approaches (e.g., DoE) to characterize processes and define robust control strategies
- Lead or support technology transfer of processes into GMP manufacturing
- Troubleshoot process challenges and drive continuous improvement in process performance
- Collaborate with Manufacturing, Analytical, Quality, Non-Clinical, and Regulatory teams to enable program advancement
- Author technical reports and contribute to CMC sections of regulatory filings and respond to agency questions.
Benefits
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year
- Employee Resource Groups participation
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
