Scientist I or II / Mass Spectrometry Screening

UCB•Cambridge, MA

4d•$99,200 - $130,200•Onsite

About The Position

We are seeking a highly motivated and independent Scientist I or II / Mass Spectrometry Screening to join our Discovery Sciences team at the UCB-Boston (Cambridge) site. This role will support early-stage programs across UCB’s therapeutic areas of interest through designing, executing, and interpreting mass spec-based assays for hit discovery and hit to lead optimization. Please note that this is a lab-based position requiring you to be onsite 5 days/week.

Requirements

MS or PhD in Analytical Chemistry, Chemistry, Biochemistry, or related discipline. Recent PhD graduates with strong hands-on AS‑MS experience are encouraged to apply
Demonstrated expertise in mass spectrometry. Direct experience with AS/MS, MS/MS, and library screening is preferred.
Prior knowledge of the relevant application area (e.g., discovery screening, protein–ligand interactions, small-molecule analysis)
Strong analytical thinking, problem‑solving, and scientific communication skills

Nice To Haves

Experience with developing and prosecuting peptide-based library screening using MS is highly preferred.
Experience with LC–MS, HRMS, and MS/MS in the context of AS‑MS workflows
Experience working in a discovery or industry research environment is a plus
Publications or conference presentations in mass spectrometry or related fields.

Responsibilities

Design, develop, and execute Affinity Selection Mass Spectrometry (AS‑MS) assays to support small-molecule and peptide screening in collaboration with discovery teams.
Work as part of a cross‑functional team to develop and deploy mass spec-based screening strategies and communicate results to drive pipeline research programs.
Generate large screening data sets and collaborate with Data Analytics team to leverage data for hit selection and SAR generation.
Maintain, troubleshoot, and improve MS instruments and workflows.
Stay current with advances in mass-spectrometry based technologies and emerging methodologies in the field.