Scientist I, Ophthalmology Research

Astellas Pharma • Westborough, MA

4d • $94,570 - $135,100 • Onsite

About The Position

The Scientist I, Ophthalmology Research supports the design, execution, and analysis of in vivo ophthalmology research studies that advance therapeutic programs from discovery through early development. The incumbent will generate high-quality data through hands-on laboratory work and collaborate within the broader research team to support program objectives. This is a bench-based role that provides opportunities to develop scientific and technical expertise in ophthalmology research and drug discovery.

Requirements

• PhD in Ophthalmology, Neuroscience, Biology, Pharmacology, or a related scientific discipline with 0-3 years of relevant postdoctoral and/or industry research experience; OR MS degree with 5+ years of relevant research experience; OR BS degree with 8+ years of relevant research experience.
• Hands-on experience conducting in vivo research studies and analyzing experimental data.
• Experience working with animal models (rat and/or mouse) and laboratory research techniques.
• Research experience in ophthalmology drug discovery, retinal biology, or related disciplines.
• Familiarity with one or more therapeutic modalities, including biologics, gene therapy, cell therapy, RNA therapeutics, or small molecules.
• Strong organizational skills, attention to detail, and ability to maintain accurate documentation.
• Demonstrated ability to work effectively in a collaborative team environment.
• Strong written, verbal, and presentation communication skills.

Nice To Haves

• Intraocular dosing techniques in rodents (i.e. subretinal injection, intravitreal injection, etc.)
• Experience with ocular imaging and visual function assessments, including OCT, fundus imaging, ERG, optomotor response, or related techniques.
• Experience with ocular histology, tissue processing, microscopy, and image analysis.
• Familiarity with translational research and drug discovery.
• Experience collaborating with external laboratories, CROs, or academic partners.
• Demonstrated ability to learn new techniques and adapt to changing project priorities.

Responsibilities

• Conduct in vivo pharmacology studies to evaluate therapeutic candidates across ophthalmology indications.
• Perform hands-on experimental activities including animal procedures such as intraocular dosing (e.g. subretinal/intravitreal injection), clinical assessments, functional/efficacy evaluation, tissue collection, and other study-related techniques.
• Analyze, interpret, document, and present experimental data with guidance from senior scientists.
• Contribute to study design, protocol development, troubleshooting, and execution of research plans.
• Assist with internally and externally conducted studies, including collaborations with cross-functional teams and contract research organizations.
• Maintain accurate laboratory records, notebooks, and study documentation in accordance with company standards.
• Communicate scientific results through presentations, reports, and team discussions.
• Contribute to a collaborative, inclusive, and scientifically rigorous work environment by sharing knowledge and working effectively with team members.
• Remain current with relevant scientific literature, technologies, and emerging approaches in ophthalmology research and drug discovery.

Benefits

• Medical, Dental and Vision Insurance
• Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
• 401(k) match and annual company contribution
• Company paid life insurance
• Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
• Long Term Incentive Plan for eligible positions
• Company fleet vehicle for eligible positions
• Referral bonus program

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree