Scientist I, High-Throughput Biology

Eikon Therapeutics•Millbrae, CA

About The Position

As a member of Eikon Therapeutics’ High-Throughput Biology Team, the Scientist I will develop drug discovery screening assays using the company’s proprietary live-cell, single-molecule high-throughput super-resolution microscopy platform. The role works across biology, automation engineering, and computational science to generate scalable, reproducible, decision-enabling biological data for drug discovery programs. The position focuses on developing, optimizing, validating, and scaling live-cell imaging-based assays, analyzing large datasets, and delivering actionable findings to project teams. The scientist will also help transition optimized processes into production workflows, maintain thorough experimental records, collaborate across scientific disciplines, and contribute to training junior scientists.

Requirements

  • Ph.D. or Master’s degree plus 10 years of relevant experience, or Bachelor’s degree plus 12 years of relevant experience, in Biology, Bioengineering, Biotechnology, or a related field.
  • Proficiency in mammalian cell culture and sterile technique.
  • Proficiency with laboratory techniques and equipment relevant to molecular and cellular biological research.
  • Demonstrated experience systematically optimizing and validating biological assays.
  • Strong analytical and troubleshooting skills with novel assay technologies.
  • Working experience in quantitative fluorescence microscopy and/or super-resolution microscopy.
  • Working experience with quantitative and/or statistical analysis using common software tools such as Microsoft Suite or GraphPad Prism.
  • Working experience with at least one high-level programming language, such as Python, MATLAB, or R, for large-dataset analysis and visualization.
  • Excellent communication skills and ability to convey scientific concepts effectively.
  • Collaborative approach and ability to work effectively in multidisciplinary teams.
  • Proactive and adaptable in response to evolving research priorities and challenges.

Nice To Haves

  • Working experience in protein dynamics using single-molecule microscopy.
  • Working experience with high-throughput instrumentation and automation systems.

Responsibilities

  • Design, execute, and analyze experiments to optimize, validate, and scale live-cell imaging-based assays for high-throughput screening using Eikon’s super-resolution microscopy platform.
  • Collaborate with computational biologists and software engineers to apply computational and statistical methods, including machine learning, to large datasets.
  • Summarize and deliver timely, high-quality, actionable data to inform decisions across drug discovery portfolios.
  • Exercise scientific judgment and provide data-driven recommendations to project teams.
  • Maintain organized, comprehensive electronic records of experiments, results, and protocols in accordance with company standards and regulatory requirements.
  • Work with the High-Throughput Biology Operations Team to transfer optimized processes into production workflows and document standard operating procedures.
  • Collaborate and communicate with biologists, chemists, and engineers.
  • Contribute to the growth and training of junior scientists.

Benefits

  • 401(k) plan with company matching.
  • Medical insurance, with premiums covered by Eikon at 95%.
  • Dental insurance, with premiums covered by Eikon at 100%.
  • Vision insurance, with premiums covered by Eikon at 100%.
  • Mental health and wellness benefits.
  • Weeklong summer and winter holiday shutdowns.
  • Generous paid time off and holiday policies.
  • Life and AD&D insurance, with premiums covered by Eikon at 100%, plus optional supplemental employee-paid policies.
  • Enhanced parental leave benefit.
  • Daily subsidized lunch program when on-site.
  • Bonus and equity compensation.
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