Scientist/Health Sciences

University of New Mexico•Albuquerque, NM

2d•$4,924 - $7,046•Onsite

About The Position

The Mandell Lab at The University of New Mexico Health Sciences Center is seeking a highly motivated and well-trained individual to join our research team as a Scientist. Our laboratory investigates the molecular mechanisms of autophagy, with a particular focus on the roles of TRIM family ubiquitin ligases. This is an exciting opportunity to contribute to cutting-edge research in cellular homeostasis and organelle quality control. Our laboratory studies how TRIM (tripartite motif-containing) proteins, a family of ubiquitin ligases, regulate autophagy and impact cellular stress responses. Using a combination of advanced imaging, molecular biology, and functional assays, we aim to uncover novel regulatory pathways that connect ubiquitination to the autophagic machinery.

Requirements

Doctorate degree; at least 1 year of post-doctorate experience directly related to the duties and responsibilities specified.
Completed degree(s) from an accredited institution that are above the minimum education requirement may be substituted for experience on a year for year basis.

Nice To Haves

Ph.D. in Cell Biology, Molecular Biology, Biochemistry, or a closely related field with 4+ years postdoctoral training.
Extensive experience in standard molecular and cell biology techniques including investigations into protein-protein interactions.
Excellent communication, organizational, and documentation skills.
A strong publication record and a commitment to rigorous, reproducible science.
Strong background in autophagy research, including familiarity with key pathways and assays.
Prior experience studying ubiquitin ligase biology.
Familiarity with automated image analysis workflows and data management.
Experience working with viruses (especially HIV) under BSL-2 or higher conditions.
Prior experience working with host restriction factors against viral infection.
Prior experience with culture of iPSC-derived neurons.

Responsibilities

Design and conduct high-quality, reproducible experiments focused on TRIM protein function in autophagy.
Utilize high-content microscopy, specifically with the CellInsight CX7 platform, to analyze cellular phenotypes.
Perform and troubleshoot a wide range of standard cell and molecular biology techniques.
Maintain detailed and organized experimental records using NIH-compliant digital lab notebooks.
Manage and organize laboratory supplies and experimental collections.
Train and mentor new laboratory members in technical protocols and lab operations.
Contribute to manuscript preparation and grant writing in collaboration with the Principal Investigator (PI).