Scientist / Engineer

Pfizer • Sanford, NC

15h • Onsite

About The Position

The Process Scientist / Engineer – Purification role in Manufacturing Science and Technology (MSAT) organization supports biological therapeutics and vaccines. Within MSAT, the incumbent works in the Purification Group, which develops processes for isolation and purification of recombinant proteins, polysaccharides, bioconjugates, and other biologics. Projects may include execution of processes at lab and pilot scales, process development and characterization, scale-up and tech transfer to commercial manufacturing, process simulation and modeling, process troubleshooting, new technology development and implementation. The incumbent will run various recovery and purification unit operations, including preparative chromatography, Tangential Flow Filtration (TFF), and Normal Flow Filtration (NFF) at lab and pilot scales, as well as providing support for commercial scale operations as needed. The scope of the project work may include tasks in any (or all) of the following stages: scope definition, feasibility studies, cost/benefit analyses, design, specification development, project planning, implementation, and post-implementation monitoring and follow-up. The incumbent must be capable of providing significant contributions to cross-functional projects and may lead some teams with involvement and coaching from their supervisor.

Requirements

• BA/BS with at least 6 years of experience or MBA/MS with at least 4 years of experience
• Degree in Chemical/Biochemical Engineering, Biochemistry, or other related biotechnology discipline
• Technical knowledge and skills in purification of biologics achieved through industrial or academic experience in research and development, technical operations, manufacturing, etc.
• Demonstrated experience with operating, monitoring, and control of purification processes including chromatography, TFF, and NFF.
• Application of knowledge of purification processes to facilitate troubleshooting and resolving process issues, diagnosing technical problems, and determining short- and long-term solutions.
• Highly motivated, self-starter, ability to work with a team or alone to achieve goals as needed.
• Always acts with integrity and in accordance with Pfizer values, company policies, procedures, and all applicable regulatory guidelines including cGMP.
• Puts safety of patients, self, and other colleagues first; complies with all safety, occupational health and environmental requirements.
• Application of knowledge/experience of the principles, concepts, and practices of a discipline
• Increasingly relies on own experience and knowledge as well as that of others for scientific judgment in work situations.
• Build and utilize network connections established on cross-functional teams to shape local project milestones and deliverables.
• Permanent work authorization in the United States.

Responsibilities

• Utilizing a high level of technical expertise, the incumbent is responsible for moderately complex projects related to the development, scale-up and/or characterization of processes, equipment, and control strategies, process optimization, qualification of alternate raw materials and components, and/or technology transfer to GMP commercial manufacturing facilities.
• Execute, analyze, document, and communicate results from experimental studies conducted at lab, pilot or commercial scales.
• Interpret data and make recommendations to optimize processes, improve yields, and enhance the smooth transition from development through to successful implementation.
• Troubleshoot and resolve process issues, diagnose technical problems, and determine short- and long-term solutions.
• Work both independently and in team environments and be able to coordinate multiple technical projects simultaneously in a well-organized fashion.
• Prepare technical reports, provide oral presentations to scientists and management, and assist in the preparation of regulatory filing documents, as required.

Benefits

• 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
• paid vacation, holiday and personal days
• paid caregiver/parental and medical leave
• health benefits to include medical, prescription drug, dental and vision coverage
• Relocation assistance may be available based on business needs and/or eligibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Associate degree