Scientist, DMPK (BioAnalytical and Medical Writing)

Cogent Biosciences•Boulder, CO
•$115,000 - $130,000•Hybrid

About The Position

This position works in Drug Discovery to provide bioanalytical support for PK, PK/PD, TK, and TGI experiments across multiple programs. The successful candidate will utilize their strong knowledge of LC-MS/MS bioanalysis to quantitate small molecule drugs in biological matrices (plasma primarily). Independent method development, routine bioanalysis, and communication of high-quality data are hallmarks for the position. Maintenance, troubleshooting, and repair of LC-MS/MS instrumentation and software is expected. Secondary roles of the position include providing technical writing support and review as needed.

Requirements

  • Minimum of BA/BS with 10 years or MS with 8 years of analytical work in Pharma/Biotech
  • LC-MS/MS
  • Independence, awareness, and multi-tasking in a fast-paced environment
  • Scientific and technical knowledge around small molecule quantitative bioanalysis
  • Strong knowledge of LC-MS/MS instrumentation, troubleshooting, method development, and quantitation
  • Microsoft Office Suite

Nice To Haves

  • Sciex QQQ or Shimadzu UPLC
  • Knowledge of DMPK and relationships of in vitro and in vivo assays
  • Non-compartmental PK modeling
  • Report writing
  • Process automation via software, robotics, or liquid handling

Responsibilities

  • Develop LC-MS/MS methods to quantitate small molecules in biological matrices
  • Routine bioanalysis and data release to DMPK project leads
  • Maintain, troubleshoot, and repair LC-MS/MS instrumentation and software, including coordination with service engineers for complex matters
  • Support technical writing efforts and data QC for preclinical ADME IND efforts
  • Good written and oral communication, including timely electronic laboratory notebook entry
  • Proven work ethic, competence, enthusiasm, independence, and team focus

Benefits

  • Competitive salary
  • Bonus
  • Ongoing stock awards
  • 100% medical, dental, and vision premiums for you and your family
  • Funding up to 75% of in-network deductibles
  • 401(k) match with immediate vesting
  • Generous paid time off
  • 12 weeks of fully paid parental leave
  • Paid family and medical leave for all employees regardless of location
  • Company-paid short-term disability coverage for up to 20 weeks
  • Wellness programs
  • Tuition reimbursement
  • Inclusive family-forming support
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