Senior Scientist, Chemistry and Delivery Science

ModernaTX • Cambridge, MA

10d • Onsite

About The Position

We are looking for an accomplished Scientist to spearhead the development of targeted lipid nanoparticle (LNP) formulations within our fast-moving, cross-functional R&D organization. In this role you will push the boundaries of LNP self-assembly, engineer delivery systems for both small- and large-molecule payloads beyond the liver and apply state-of-the-art analytical techniques to link structure with biological performance.

Requirements

• Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Materials Science, or a related discipline with 2+ years of experience.
• Deep expertise in lipid nanoparticle design, formulation, and characterization; hands-on experience developing targeted or extra-hepatic LNPs preferred
• Proficiency with a broad suite of analytical techniques for nanoparticle size, morphology, composition, and stability assessment
• Demonstrated ability to plan and manage multiple projects in a highly collaborative, fast-paced setting
• This position is site-based, requiring you to be at Moderna’s site full-time.
• This position is not eligible for remote work
• Only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position.

Nice To Haves

• Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Materials Science, or a related discipline with 2+ years of experience.
• Deep expertise in lipid nanoparticle design, formulation, and characterization; hands-on experience developing targeted or extra-hepatic LNPs preferred
• Proficiency with a broad suite of analytical techniques for nanoparticle size, morphology, composition, and stability assessment
• Demonstrated ability to plan and manage multiple projects in a highly collaborative, fast-paced setting
• Clear, concise scientific communication—written and verbal—with a track record of peer-reviewed publications and/or patents
• Commitment to inclusive teamwork, continuous learning, and high scientific rigor
• Experience with high-throughput methodologies is highly desirable, and familiarity with artificial intelligence and machine learning techniques is considered a strong plus

Responsibilities

• Drive research programs on targeted, extra-hepatic LNP delivery—from hypothesis generation through in-vitro / in-vivo evaluation
• Develop and optimize LNP self-assembly processes; refine composition, payload loading, and surface modifications for tissue and cell-type specificity
• Independently Design and execute experiments; analyze, interpret, and clearly communicate data to multidisciplinary project teams and leadership
• Implement and innovate advanced physicochemical and biophysical characterization methods (e.g., DLS, CryoEM, SAXS, ITC, NMR, nFCM etc) to elucidate structure–function relationships
• Maintain rigorous electronic laboratory notebooks, SOPs, and study documentation consistent with company expectations
• Mentor & collaborate with research associates, and external partners to meet project milestones

Benefits

• Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
• Family planning benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investment opportunities to help you plan for the future
• Location-specific perks and extras

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree