Scientist - Bispecifics and Antibody Engineering
About The Position
At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a results-driven Scientist to join our Bispecifics and Antibody Engineering Department, supporting the production, purification, and functional characterization of next-generation antibodies across multiple programs. In this role, your work will directly impact the therapeutic pipeline while contributing to the development of new platform capabilities, in a fast-paced environment alongside diverse, cross-functional teams. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.
Requirements
- B.Sc., M.Sc., or related degree in molecular biology, cell biology, biochemistry, immunology, or a related field, with 5+ years of relevant academic or industry experience
- Strong attention to detail and a rigorous approach to experimentation
- Excellent organizational, communication, and presentation skills
- Ability to prioritize and adapt quickly to evolving program directions and timelines
Nice To Haves
- hands-on experience with cloning, antibody expression, antibody purification and characterization, and cell-based bioassays
- experience with in vivo disease modeling
Responsibilities
- Perform molecular biology techniques to generate expression constructs, including DNA isolation and sequence confirmation
- Conduct transfections for protein production at multiple scales
- Purify biologics using chromatography platforms, including affinity, ion exchange (IEX), and size-exclusion chromatography on ÄKTA systems
- Characterize proteins via immunoblotting, SDS-PAGE, thermal stability, and UV/Vis spectrophotometry
- Perform properly controlled biochemical and cell-based assays (e.g., ELISA, AlphaLISA, flow cytometry, phagocytosis, cell activation, and cytolytic assays)
- Troubleshoot bioanalytical and cell-based assay data to inform iterative optimization
- Collaborate with colleagues to evaluate biological function in vivo
- Maintain accurate records in Benchling and electronic lab notebooks (ELN)
Benefits
- annual bonuses or other incentive plans
- equity awards
- pension or retirement benefits
- 401(k) company match
- health and wellness programs
- fitness centers
- insurance benefits (e.g. medical, dental, vision, life and disability)
- paid time off
- family support benefits
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What This Job Offers
Job Type
Full-time
Career Level
Senior
