Scientist, Biologics Purification
About The Position
Join AbbVie’s Biologics Discovery Sciences group and make a tangible impact in advancing innovative biologic therapies. As a scientist specializing in Biologics Purification, you will play a pivotal role in driving drug discovery, collaborating within a dynamic team dedicated to supporting transformative science that improves patient lives worldwide. You will leverage your expertise to deliver high-purity multi-specific antibody-based biologic candidates with suitable purity/characteristics to support the advancement of vital in vitro (i.e. drug-like property assays, binding, cell-based assays, etc.) and in vivo studies (i.e. efficacy, non-GLP NHP PK, DRF, etc.).
Requirements
- BS or MS in Biochemistry, Biophysics, Biomedical, Chemical Engineering, or a related field, with typically 5-7 years (BS) or 2-5 years (MS) of experience
- Demonstrated expertise in preparative-scale column chromatography techniques (i.e. affinity, IEX, HIC, multimodal) for antibody-based biologics purification
- Hands-on experience operating AKTA chromatography systems and Unicorn software
- Strong foundation in analytical characterization techniques, including HPLC, gel electrophoresis, ELISA, mass spectrometry, and related methods
- Solid understanding of protein structure, molecular attributes and post-translational modifications impacting biologic quality and performance
- Excellent written, verbal, and presentation skills, with the ability to communicate complex scientific concepts to diverse audiences
- Track record of scientific curiosity, innovation, and continuous learning
- Collaborative mindset with a passion for teamwork, scientific rigor, and delivering impactful solutions
Nice To Haves
- Knowledge of biologics manufacturing or process development is a plus
Responsibilities
- Lead end-to-end purification campaigns at production-based scales for delivery of high-quality multi-specific antibody biologics to support critical research efforts and program decisions
- Design and optimize downstream purification strategies using advanced chromatography techniques to remove process impurities, mitigate product liabilities, and achieve target quality attributes
- Apply deep analytical expertise to characterize molecules, process intermediates, impurities, and final drug candidates, enabling data-driven process decisions
- Drive scientific innovation and continuous process improvement by identifying and implementing novel approaches that enhance downstream biologics development workflows
- Partner across multidisciplinary teams, translating process insights into functional results to accelerate the advancement of therapeutic candidates
- Communicate scientific findings with clarity and influence, presenting technical information to diverse audiences to support project progression and knowledge sharing
Benefits
- paid time off (vacation, holidays, sick)
- medical/dental/vision insurance
- 401(k)
- short-term incentive programs
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Associate degree
