Downstream Purification Scientist

Ecolab Inc.•Upper Merion Township, PA
•$96,700 - $145,100

About The Position

Ecolab is seeking a Downstream Purification Scientist to develop chromatography processes and advance technical platforms that meet both business and customer needs. In this position, you will be responsible for conducting and leading chromatography experiments aimed at the industrial purification of monoclonal antibodies. You will collaborate closely with field and laboratory-based technical teams to design, execute, and communicate results from process development studies. We are looking for candidates who demonstrate strong collaboration and teamwork skills, are self-motivated, possess excellent communication abilities, are adept at creative problem-solving, and have keen observation and perception skills.

Requirements

  • BS required – Biochemistry, Chemical Engineering, Biotechnology, Biology, Chemistry or related degree
  • Five years of demonstrated experience in ‘chromatography process development’ for commercial scale purification of antibodies is a must-have.
  • Demonstrated strong theoretical and fundamental knowledge of chromatography
  • The ability to exhibit a high level of attention to detail and a quality-minded approach to all record keeping

Nice To Haves

  • MS in Biochemistry, Chemical Engineering, Biotechnology, Biology, Chemistry or related degree preferred
  • Ability to lead small lab-based teams preferred
  • Strong problem-solving skills
  • Strong oral and written communication skills
  • Understanding of fundamental physical/chemical properties and structural activity relationships
  • Working knowledge of statistics

Responsibilities

  • Provide technical support by demonstrating strong theoretical and fundamental knowledge, in addition to practical applications, specifically chromatography, and other downstream unit operations, in general.
  • Routinely author protocols and reports for chromatography studies for purification of monoclonal antibodies.
  • Design, establish and execute bench-scale applications experiments using AKTA and other bench-scale chromatography systems.
  • Perform process screening and optimization experiments using a Tecan Te-Chrom high-throughput system.
  • Analyze samples using HPLC, SDS-PAGE, ELISA, PCR, spectrophotometry and other appropriate analytical tools to determine product purity and non-product related impurity profile.
  • Maintaining accurate records and interpreting data to provide detailed information and analysis on the execution of experiments
  • Solid critical thinking skills with the ability to communicate technical issues, resolve complex problems and propose efficient and robust solutions.
  • Follow all procedures established in the lab to ensure efficiency and safety.
  • Must be able to lift up to 25 pounds at times.

Benefits

  • Annual bonus pay based on performance, per plan terms.
© 2026 Teal Labs, Inc
Privacy PolicyTerms of Service