Scientist, Analytical R&D

NJ BIO INC•Princeton, NJ

7d•$70,000 - $110,000•Onsite

About The Position

The Scientist, Analytical R&D works under minimal supervision on analytical methods for the characterization of small and large molecules, including linker payloads and antibody-drug conjugates (ADCs). The role involves developing, optimizing, troubleshooting, qualifying, and validating methods using techniques such as liquid chromatography, capillary electrophoresis, gas chromatography, and mass spectrometry. The scientist works with internal departments and external resources on analytical research and supports compliance with applicable regulatory requirements, company SOPs, quality standards, and EHS requirements. The position supports analytical needs across bio-conjugation, process and product development, in-process monitoring, and stability studies for APIs, drug substances, and bioconjugates. It includes documenting and communicating results, preparing technical presentations and reports, maintaining laboratory equipment and supplies, and providing general laboratory support. The work is based in an office and laboratory environment at the company's New Jersey headquarters.

Requirements

Ph.D. in Analytical Chemistry, Organic Chemistry, Biochemistry, or a related area with 0–3 years of industry experience, or a master's degree in Chemistry or a relevant field with 3–5 years of experience.
At least 1 year of GMP experience.
Practical experience with some or all of LC techniques, capillary electrophoresis, and GC for analytical method development, optimization, and validation.
Proven track record in analytical method development, project leadership, and problem solving in the pharmaceutical or biotechnology industry.
Ability to develop and execute analytical methods independently and collaboratively, including authoring and reviewing methods, protocols, and reports.
Ability to support multiple projects and prioritize changing needs and deadlines.
Ability to communicate scientific data effectively through presentations, protocols, test methods, and reports, internally and externally.
Ability to maintain safe work practices and comply with company EHS and quality standards, regulations, policies, procedures, and mission.
Effective communication with supervisors, colleagues, clients, and vendors.
Proficiency with Microsoft Office.
Excellent verbal and written communication skills.
Ability to work independently and collaboratively in a team environment with internal and external team members.
Strong analytical thinking and problem-solving skills, adaptability, planning, organization, and time management.
Ability to work outside normal business hours, including occasional nights, weekends, or holidays, as needed.

Nice To Haves

Experience applying separation, compendial, and spectroscopic techniques to characterize linker payloads and ADCs, including HPLC (RP, SEC, HIC, IEX), gel electrophoresis, and capillary electrophoresis (CE, cIEF).

Responsibilities

Develop, optimize, troubleshoot, qualify, and validate analytical methods using techniques including LC, mass spectrometry, capillary electrophoresis, and GC.
Apply routine and specialized analytical techniques to characterize and quantify small molecules, including linker payloads and ADCs.
Maintain reagent supplies and laboratory notebooks; summarize results in written reports and communicate observations in a timely manner.
Comply with quality principles related to data generation and reporting.
Prepare and deliver technical presentations internally and externally, and participate in scientific discussions.
Stay current with scientific literature in relevant areas.
Author analytical test methods, protocols, reports, and other documents.
Maintain laboratory equipment, order laboratory supplies, and provide general laboratory support.
Support analytical work for bio-conjugation, process development, product development, in-process monitoring, and stability studies.
Perform other tasks and assignments as directed by management.