Scientist - Analytical Method Development SMDD Foundry Readiness

Lilly • Indianapolis, IN

1d • $66,000 - $171,600 • Onsite

About The Position

Lilly’s Synthetic Molecule Design and Development group is seeking an analytical chemist to support development of drug candidates from early development through manufacturing readiness. This hands-on laboratory role involves more than 70% bench work. The scientist will develop analytical methods, characterize chemical processes, apply chromatographic expertise and complementary techniques such as mass spectrometry and NMR, and partner with synthetic chemists and process engineers to address process development challenges. The role requires translating analytical data into actionable insights for project teams.

The position is based at Lilly Technology Center-North in Indianapolis, Indiana. Potential exposure includes chemicals, allergens, and loud noises. Travel is 0 to 10%.

Requirements

• Bachelor’s degree in Analytical Chemistry, Biochemistry, Chemistry, or a related field.
• At least 2 years of relevant experience.
• Authorization to work in the United States on a full-time basis; Lilly will not support or sponsor work authorization or visas for this role.

Nice To Haves

• Experience developing or validating chromatographic methods (LC, GC, or IC) in pharmaceutical, chemical, or regulated-industry settings.
• Working knowledge of mass spectrometry (LC-MS, GC-MS) and NMR spectroscopy.
• Familiarity with chemical process development, synthetic organic chemistry, and the rationale for establishing material specifications and testing plans.
• Experience troubleshooting and maintaining analytical instrumentation.
• Scientific leadership and ability to influence others.
• Ability to balance multiple responsibilities, prioritize activities, and navigate ambiguity.

Responsibilities

• Develop and optimize analytical methods to measure purity, potency, and other critical quality attributes of small-molecule drug substances and synthetic intermediates.
• Select and implement appropriate analytical techniques, including HPLC, GC, NMR, and MS, to support chemical process development.
• Generate data to elucidate reaction mechanisms, characterize kinetic behavior, and identify process-related impurities.
• Collaborate with synthetic chemists and process engineers to ensure methods guide development activities and can be transferred to GMP laboratories for routine testing and manufacturing support.
• Perform laboratory work with strong attention to safety and technical rigor, following local policies and procedures.
• Apply scientific concepts and problem-solving skills while contributing across multiple projects.
• Communicate technical findings and their business implications in writing and verbally.

Benefits

• Company bonus, depending in part on company and individual performance.
• Eligibility to participate in a company-sponsored 401(k).
• Pension.
• Vacation benefits.
• Eligibility for medical, dental, vision, and prescription drug benefits.
• Flexible benefits, such as healthcare and dependent day care flexible spending accounts.
• Life insurance and death benefits.
• Certain time-off and leave-of-absence benefits.
• Well-being benefits, including an employee assistance program, fitness benefits, and employee clubs and activities.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level