Scientist 2, Single Cell Assay Development
About The Position
We are seeking an experienced and driven scientist to join the Single Cell Biology group in a full-time role, leading the development and optimization of single cell assays. This role leads hands-on molecular biology efforts to develop, test, and refine 10x single cell workflows, and provides advanced troubleshooting support for internal teams and customers. You will work in a fast-paced, multidisciplinary environment alongside colleagues in Molecular/Cell Biology, Chemistry, Fluidics, and Computational Biology, and will begin providing technical guidance to junior team members. Candidates must have hands-on experience with 10x single cell assays, deep expertise in NGS and molecular biology techniques, and the ability to independently troubleshoot complex systems.
Requirements
- B.S./M.S. or Ph.D. in chemistry, molecular biology, biochemistry, cell biology, or a related field
- B.S./M.S. with 7+ years, or Ph.D. with 3+ years, of relevant biotechnology or pharmaceutical industry experience
- Exceptional proficiency in molecular biology techniques, including nucleic acid extraction, PCR/qPCR, and NGS library preparation
- Direct, demonstrable experience with advanced molecular technologies, particularly Next-Generation Sequencing (NGS) workflows
- A proven track record of using, optimizing, and troubleshooting molecular biology protocols
- Experience with experimental design and statistical data analysis
- Ability to perform complex multi-step experiments with detailed and diligent attention to planning, organization, hands-on technique, and record keeping
- Experience working with challenging clinical sample types (e.g., FFPE tissue, primary tumor cells, low-input samples)
- Strong collaboration and communication skills, with the ability to manage priorities and begin mentoring others
- Desire to work in a flexible, fast-paced startup environment
Nice To Haves
- Hands-on experience running 10x single cell assays across a range of sample types
- Experience with the product development lifecycle, including new product introduction and familiarity with formal product testing (e.g., verification and validation)
- Experience mentoring junior scientists or research associates
Responsibilities
- Lead the testing and troubleshooting of new assay sub-systems and existing single cell workflows, including sample processing, library preparation, sequencing, and data analysis
- Prepare high-quality NGS libraries and independently optimize established molecular biology protocols
- Contribute to the conception and implementation of solutions to complex technical challenges, and contribute to design decisions for new assay systems
- Master the use of existing tools and defined methods, and lead their improvement
- Conceive of and develop new tools and methods to advance assay development capabilities
- Analyze and interpret experimental data to draw conclusions and determine next steps
- Generate intra-functional and cross-functional project sub-task plans, and contribute to broader project plans
- Begin to provide technical guidance to junior functional team members
- Partner with R&D, Support, and Marketing to drive assay development priorities and customer-facing troubleshooting
Benefits
- equity grants
- comprehensive health and retirement benefit programs
- annual bonus program or sales incentive program
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
