Researcher

University of Oklahoma•Oklahoma City, OK

22h

About The Position

The Stephenson Cancer Center is seeking a highly motivated Researcher to support laboratory and translational research programs focused on multiple myeloma, CAR-T cell therapy, hematopoietic toxicity, and cellular immunotherapy. The role involves designing and conducting experiments, generating high-quality scientific data, supporting cellular therapy manufacturing and quality control processes, and contributing to publications and research funding initiatives. The Researcher will conduct complex laboratory procedures and maintain accurate records; support cellular therapy research and manufacturing using the Miltenyi CliniMACS Prodigy system; and perform in-process and release quality control testing under cGMP and FACT standards. Laboratory techniques include flow cytometry using MACSQuant platforms, qPCR and ddPCR analyses, cell counting and viability assessments, and sample processing and characterization. The position also involves analyzing and communicating scientific findings, preparing figures and reports, contributing to manuscripts and funding proposals, and supporting laboratory operations, supply management, safety, quality standards, and institutional compliance. The role may require working in classified cleanroom environments for extended periods and balancing scheduled manufacturing runs with ongoing research projects.

Requirements

Doctoral or terminal degree in a relevant discipline, or a master's degree in a relevant discipline plus 2 years of relevant research experience as a substitute.
Proficiency in aseptic technique and mammalian or primary cell culture.
Experience with flow cytometry and qPCR/RT-qPCR, including data analysis.
Familiarity with regulated or quality-driven work, such as cGMP, GLP, FDA, or ISO medical device quality systems, and good documentation practices, or demonstrated ability to learn them quickly.
Ability to gown for and work in classified cleanroom environments for extended periods.
Ability to manage competing priorities between scheduled manufacturing runs and ongoing research projects.

Nice To Haves

A master's degree in biology, biomedical engineering, immunology, or a related field with 2 or more years of hands-on laboratory experience, including graduate research; or a bachelor's degree with 3 or more years of experience.
Familiarity with FACT-JACIE standards, AABB, CAP/CLIA, or FDA IND-phase manufacturing.
Experience with assay qualification or validation, environmental monitoring, and deviation/CAPA systems.
Certification such as MLS(ASCP), MB(ASCP), or CQA.

Responsibilities

Plan, design, and execute experiments supporting translational and laboratory-based cancer research programs.
Perform complex laboratory procedures and maintain accurate research records.
Generate high-quality, reproducible data for scientific investigations.
Support research on multiple myeloma, CAR-T cell biology, cellular immunotherapy, and hematopoietic toxicity and recovery.
Operate the Miltenyi CliniMACS Prodigy system for cellular therapy and translational research initiatives.
Perform in-process and release quality control testing under cGMP and FACT standards.
Conduct flow cytometry using MACSQuant platforms, qPCR and ddPCR analyses, cell counting and viability assessments, and sample processing and characterization.
Analyze, interpret, and summarize scientific data.
Present findings to investigators, research teams, and scientific audiences.
Prepare figures, reports, and scientific documentation.
Contribute to manuscript preparation and peer-reviewed publication efforts.
Assist with research funding proposals, grants, and related documentation.
Procure and maintain laboratory supplies, reagents, and equipment.
Assist with inventory management and operational planning.
Ensure compliance with laboratory safety requirements, quality standards, and institutional policies.
Support efficient laboratory workflows and maintain organized research environments.