Researcher or Senior Researcher - Geeleher Lab - Department of Computational Biology

St. Jude Children's Research Hospital•Memphis, TN

6d•Onsite

About The Position

The laboratory of Dr. Paul Geeleher is seeking a wet-lab Researcher or Senior Researcher to support work on mechanistic dissection of hits from high throughput drug and CRISPR screens, the development of new drug combinations, and mechanistic dissection of drug resistance mechanisms in neuroblastoma. Dr. Geeleher’s laboratory tightly integrates wet-bench and computational approaches, aimed at improving outcomes in pediatric cancers, especially neuroblastoma. The group has spearheaded publications in Nature, Genome Biology, Journal of the National Cancer Institute (JNCI), and Nature Communications, and is funded by the NIH (R01, R00, R35 awards). They are also closely integrated into the Pediatric Cancer Dependency Map (PedDep), a large multi-institutional collaboration between St. Jude, Dana Farber and the Broad Institute, aimed at discovering new therapeutic targets and drug repurposing opportunities in pediatrics. This position is located in Memphis, TN and is a 100% on-site position with relocation assistance available.

Requirements

Bachelor's degree in relevant scientific area is required.
For Senior Researcher: Two (2) years of research experience is required with a bachelor's degree.
For Senior Researcher: No prior experience is required with a Master's degree.
Working knowledge and understanding of underlying concepts and principles of experimental design.
Experience with the most widely used techniques used in the home laboratory.
Proven performance in earlier role/comparable role.
Familiarity with Microsoft Excel, PowerPoint, and Word software.
Good written and spoken English and presentation / communication skills.
A strong interest in experimental cancer biology and dedication to scientific rigor is essential.

Nice To Haves

Prior hands-on experience with standard molecular biology techniques such as cell culture, PCR, qPCR/RT-qPCR, DNA and RNA isolation, molecular cloning, transfection and lentiviral transduction, and Western blotting.
Experience with preclinical models is desirable.
Experience in pediatric cancer, especially neuroblastoma, is desirable but not required.

Responsibilities

Supporting complex research projects and contributing to resulting publications.
Performing standard cell and molecular biology assays, with guidance as needed from senior lab members.
Learning and implementing new assays as needed given the research direction.
Supporting a research project and contributing to drafting a manuscript.
Working collaboratively with senior scientists and other lab members.
Performing other related duties as assigned in order to meet the goals and objectives of the department and the institution.
Maintaining regular and predictable attendance.