Research Technologist (Department of Medicine- Infectious Diseases)

Johns Hopkins University•Baltimore, MD

7d•$16 - $27•Onsite

About The Position

The Research Technologist assists the Center for Tuberculosis Research with studies evaluating new drugs and drug combinations in in vitro and mouse models of mycobacterial lung infection. Under direct supervision, the role is assigned projects involving stepwise assessment of microbiologic efficacy, drug pharmacokinetics, and drug resistance. The position performs laboratory tasks and routine assays using established protocols and procedures. The technologist supports in vitro and animal studies evaluating drug candidates; cultivates pathogenic bacteria, including M. tuberculosis and non-tuberculous mycobacteria; and handles biohazardous materials under BSL-2 and BSL-3 conditions. The work also includes animal infections and treatment, mouse necropsies, collection of infected organs, bacterial drug susceptibility testing, and mutational analysis. The technologist collects and analyzes data, maintains laboratory equipment and supplies, and collaborates with research colleagues and vendors. The position reports data and troubleshooting needs to the PI in weekly meetings.

Requirements

Bachelor's degree in Biology, Chemistry, or a related field.
Additional education may substitute for required experience, and additional related experience may substitute for required education beyond a high school diploma or equivalent, as permitted by the JHU equivalency formula.

Nice To Haves

Some related post-undergraduate work experience.

Responsibilities

Perform clinical and/or research laboratory experiments using common protocols, independently or with instructions.
Learn laboratory techniques and methods using basic science knowledge and develop problem-solving skills through training and experience.
Run laboratory tests, complete measurements, and identify and resolve common problems in routine assays.
Set up experiments based on defined standards and collect project data.
Train users in standard equipment operation and routine laboratory techniques and procedures.
Prepare, test, and maintain standard laboratory equipment; perform laboratory maintenance; monitor supplies; and clean equipment.
Coordinate and support in vitro and animal studies evaluating new drug candidates.
Collect, organize, and analyze experimental data.
Assist with cultivation of pathogenic bacteria, including M. tuberculosis and non-tuberculous mycobacteria.
Handle biohazardous materials under BSL-2 and BSL-3 conditions.
Perform aerosol infections in animals and administer treatments by injection or oral gavage.
Conduct mouse necropsies and collect infected organs for culture and genetic analysis.
Perform drug susceptibility testing and mutational analysis on bacterial isolates.
Collaborate with faculty, staff, students, postdocs, and vendors.
Meet weekly with the PI to review data, troubleshoot experiments, and prioritize work.
Maintain training records, inventory, laboratory supplies, and purchasing paperwork.