Research Technologist II
About The Position
The Ivy Brain Tumor Center is a pioneering non-profit clinical research program dedicated to developing transformative therapies for patients with aggressive brain tumors. As a global leader in early-phase neuro-oncology trials the Center hosts the largest portfolio of Phase 0 studies for brain tumors worldwide. Our multidisciplinary team integrates clinical care translational science and precision medicine to accelerate the identification and development of first-in-class therapies. We are seeking a highly motivated Research Tech II to join our translational neuro-oncology research team. This role is ideal for an individual with strong laboratory experience who is capable of independently executing complex experimental workflows. The successful candidate will play a key role in advancing innovative liquid biopsy platforms to study pharmacogenomic response tumor evolution and disease progression.
Requirements
- Bachelor’s degree in biological sciences or a related field
- Two (2) years prior experience in a research, clinical, or other scientific environment
- Prior laboratory research experience with demonstrated proficiency in cell culture, molecular biology techniques (e.g. PCR, qPCR) and/or sequencing library preparation
- Strong analytical and problem-solving skills with the ability to learn and execute new techniques independently
- Excellent attention to detail, organization and time management
- Strong written and verbal communication skills
Nice To Haves
- Four (4) years of prior experience in a research, clinical, or other scientific environment
- Background in cell biology, neuroscience or oncology
- Familiarity with CLIA-regulated workflows and liquid biopsy methodologies
- Experience with single-cell RNA sequencing and next-generation sequencing platforms
Responsibilities
- Perform standard laboratory procedures with some independence, under the general supervision of a PI or Research Technician.
- Execute experimental protocols, collect/record data, and maintain lab equipment.
- Perform complex procedures and provide guidance to students.
- Receive, process, and manage biospecimens—including tumor tissue, cerebrospinal fluid (CSF), and blood—in compliance with CLIA-regulated protocols.
- Isolate cell-free DNA from CSF and extract genomic DNA from tumor tissue and peripheral blood.
- Isolate circulating cells from CSF and perform tissue dissociation for downstream applications.
- Prepare single-cell RNA sequencing libraries using the 10x Genomics platform from tumor and CSF-derived cells.
- Generate DNA sequencing libraries from tumor tissue, blood, and cell-free DNA.
- Maintain rigorous, accurate documentation of experimental workflows in accordance with established protocols and regulatory standards.
- Contribute to a collaborative research environment through participation in lab meetings, seminars, and journal clubs.
- Keeps accurate records of studies conducted with minimal supervision.
- Performs basic data analysis and processing as required by senior laboratory personnel.
- Creates, maintains, and updates lab's internal procedure manuals.
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
