Research Technician

Mass General Brigham•Boston, MA

9h•Onsite

About The Position

Dr. Edlow’s basic and translational research in the Vincent Center for Reproductive Biology (VCRB) at Massachusetts General Hospital focuses on neurodevelopmental and metabolic programming effects of maternal immune activation in pregnancy (either by obesity, maternal high-fat diet, or viral/bacterial infections in pregnancy). The work is both with mouse models and with human samples (maternal and cord blood, placenta, breastmilk, among others). Our laboratory performs highly collaborative, multi-disciplinary research that spans the fields of developmental biology, immunology, infectious diseases, metabolism, and neuroscience. The Research Technician reports directly to the Principal Investigator and is expected to work independently on assigned research with guidance from a higher-level lab member (e.g. Research Scientist, Postdoctoral Fellow) and/or the Principal Investigator. Experience with tissue dissection and preservation for RNA and immunohistochemical analyses, molecular techniques such as DNA/RNA extraction from tissues, and tissue sectioning and staining is preferred but not required. The Technician will assist with the laboratory’s ongoing research projects studying the neurodevelopmental and metabolic programming effects of immune activation (via obesity, high-fat diet and/or viral infection) in pregnancy and lactation, using both mice and mouse tissues, and samples from human research participants (examining impacts of both viral infection and/or vaccination in pregnancy). With broad guidance from the supervisor, the Technician will learn to independently perform experiments to accomplish laboratory research goals. In addition, s/he/they will be responsible for documenting, analyzing, and reporting the results derived from mouse models and/or patient samples. The Technician may assist in the preparation of manuscripts for publication, with opportunities for authorship and mentorship in writing scientific papers if desired. The individual will also assist with gathering information needed for grant preparation and reporting and must be proficient in basic computer skills including word-processing, database and spreadsheet management, email and internet. Our laboratory is committed to diversity, equity and inclusion, and we foster an environment that is inclusive and welcoming to individuals of all backgrounds and experiences. Underrepresented minorities in science and medicine are encouraged to apply. Summary Responsible for maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data. Candidates who are in the process of completing their bachelor's degree have a grace period of six months from their hire date (up to 1 year if starting per diem) to provide degree equivalency verification.

Requirements

Bachelor's Degree Related Field of Study required
Prior laboratory experience, either through academic coursework, internships, or employment 1-2 years preferred
Strong theoretical and practical knowledge of laboratory techniques and procedures.
Familiarity with common laboratory equipment and instruments used in research experiments.
Proficiency in data collection, analysis, and scientific software tools.
Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
Strong problem-solving skills and the ability to troubleshoot technical issues.
Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.
Proficient in basic computer skills including word-processing, database and spreadsheet management, email and internet.

Nice To Haves

Experience with tissue dissection and preservation for RNA and immunohistochemical analyses, molecular techniques such as DNA/RNA extraction from tissues, and tissue sectioning and staining is preferred but not required.

Responsibilities

Perform laboratory experiments following established protocols and procedures.
Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
Record experimental data accurately and maintain organized records of procedures, protocols, and results.
Compile and analyze data using appropriate statistical and analytical methods.
Assist in data interpretation and presentation, contributing to research findings and reports.
Maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data.