Research Technician III - Lindell Lab & Henrickson Lab

Children’s Hospital of Philadelphia•Philadelphia, PA

5d•$47,020 - $58,780•Onsite

About The Position

This role participates in planned research projects by performing research protocols with minimal direction and guidance from the principal investigator, program director or senior scientists. May exercise moderate discretion and judgement in the execution and interpretation of experiments, and of data derived. A Research Technician III position is available jointly in the laboratories of Dr. Robert (Brad) Lindell and Dr. Sarah Henrickson at the Children’s Hospital of Philadelphia. This role is designed for a highly motivated technician interested in human immunobiology at the intersection of critical illness and genetic immune dysregulation, with protected effort and mentorship spanning two complementary but distinct research programs. The Lindell Lab (Sepsis Immunobiology) studies immune dysregulation, immune recovery, and immunometabolic dysfunction in pediatric sepsis and sepsis-associated multiple organ dysfunction syndrome (MODS), applying high-dimensional immune profiling and systems immunology to samples from prospectively enrolled critically ill children. The Henrickson Lab (Inborn Errors of Immunity) focuses on inborn errors of immunity (IEIs) and primary immune regulatory disorders, particularly diseases involving JAK/STAT pathway dysregulation, integrating patient-derived samples, advanced cellular immunophenotyping, functional assays, and multi-omic approaches. Together, these programs create a unique training environment bridging acquired immune dysfunction in critical illness and genetically mediated immune dysregulation, with strong conceptual and technical overlap.

Requirements

High School Diploma / GED - Required
At least two (2) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience - Required
Advanced understanding of lab procedures, protocols, and equipment.
Intermediate proficiency with lab specific experiments / techniques.
Intermediate scientific analysis skills.
Excellent verbal and written communications skills
Excellent organizational skills
Strong critical thinking / problem-solving skills
Strong analytical skills

Nice To Haves

Bachelor's Degree - Preferred
At least three (3) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience - Preferred

Responsibilities

Independently perform complex immunological assays using fresh and cryopreserved human biospecimens
Conduct high-dimensional spectral flow cytometry–based phenotyping and functional assays
Support multi-omic workflows, including transcriptomic and proteomic sample preparation
Maintain rigorous experimental documentation, sample tracking, and quality control
Work collaboratively across both laboratories while receiving direct mentorship from both PIs
Contribute to project planning, data interpretation, and scientific manuscripts, depending on experience and interest
Performs research procedures on experimental samples with minimal supervision
Formulates and performs complex lab experiments and analyzes/ reports the data
Performs tasks that require knowledge of advanced techniques and lab equipment
Performs advanced calculations and maintains appropriate log and lab notebooks
Assists with planning specific research protocols and procedures
Assists in development & troubleshooting of new techniques and ideas
May be required to modify scientific methods and protocols (in conjunction with PI)
Checks others' results for completeness and accuracy
May be responsible for training and mentoring new staff
May assist in the preparation of grants journal articles, posters and oral presentations
May perform routine and non-routine tests / experiments as needed
Maintains office, lab area, reagents, supplies and equipment
Performs routine maintenance on lab equipment
Coordinates schedules of tests & procedures
Attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques
Records results, organizes data and maintains lab notebook in an organized manner
Conducts literary searches as required