Research Technician I

Mass General Brigham•Boston, MA

13h•Onsite

About The Position

The Morini Laboratory at the Center for Genomic Medicine, Massachusetts General Hospital (MGH), is seeking a highly motivated Research Technician to support ongoing translational research focused on developing gene editing and pharmacological therapies for Familial Dysautonomia (FD), a rare neurodegenerative disorder. The successful candidate will play a key role in testing novel gene editing approaches and small-molecule compounds in a mouse model of FD. Responsibilities include conducting efficacy studies, genotyping, tissue processing, behavioral assays, and molecular biology techniques such as qPCR, Western blotting, and RNA analysis. We are looking for a results-driven, team-oriented individual who thrives in a fast-paced and collaborative environment. The ideal candidate is detail-oriented, self-motivated, and comfortable working independently at the bench. A background or strong interest in neuroscience, human genetics, and/or therapeutic development is highly desirable. Prior experience with mouse handling and colony management is strongly preferred.

Requirements

Bachelor's Degree in a related field of study.
Prior laboratory experience, either through academic coursework, internships, or employment.
Strong theoretical and practical knowledge of laboratory techniques and procedures.
Familiarity with common laboratory equipment and instruments used in research experiments.
Proficiency in data collection, analysis, and scientific software tools.
Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
Strong problem-solving skills and the ability to troubleshoot technical issues.
Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.

Nice To Haves

Background or strong interest in neuroscience, human genetics, and/or therapeutic development.
Prior experience with mouse handling and colony management.

Responsibilities

Perform laboratory experiments following established protocols and procedures.
Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
Record experimental data accurately and maintain organized records of procedures, protocols, and results.
Compile and analyze data using appropriate statistical and analytical methods.
Assist in data interpretation and presentation, contributing to research findings and reports.