Research Technician I

Mass General Brigham•Boston, MA

23h•Onsite

About The Position

The laboratory of Dr. Haobo Li at MGH is seeking a full-time Research Technician I to perform: (1) Basic molecular biology, (2) Cell culture methods, and (3) Small animal work. The lab studies the pathophysiology of heart disease with a growing focus on crosstalk between heart and brain. Our investigations focus on fundamental cellular processes such as cell growth, survival and regeneration, as well as on the identification and validation of new therapeutic targets. Effects of genetic, pharmacological, and physiological (e.g., exercise) interventions are explored using high throughput profiling and screening techniques as well as mechanistic studies in mouse and cell culture models. Several promising therapeutic targets have come out of our work, including intracellular and intercellular signaling proteins and non-coding RNAs. The selected candidate will join a group of talented and motivated basic and clinician scientists whose work has direct translational applications.

Requirements

Bachelor's Degree in a related field of study required.
Prior laboratory experience, either through academic coursework, internships, or employment.
Strong theoretical and practical knowledge of laboratory techniques and procedures.
Familiarity with common laboratory equipment and instruments used in research experiments.
Proficiency in data collection, analysis, and scientific software tools.
Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
Strong problem-solving skills and the ability to troubleshoot technical issues.
Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.

Nice To Haves

1-2 years of prior laboratory experience preferred.

Responsibilities

Perform laboratory experiments following established protocols and procedures.
Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
Record experimental data accurately and maintain organized records of procedures, protocols, and results.
Compile and analyze data using appropriate statistical and analytical methods.
Assist in data interpretation and presentation, contributing to research findings and reports.
Rodent work (genotyping, pharmacological, and behavioral measurements etc.)
Molecular biology/biochemical techniques (e.g, qPCR and Western blot, DNA subcloning, CRISPR-based genome editing, immunohistochemistry, histology, and enzyme assays, as well as data collection and analysis).