UNIV - Research Specialist II - Regenerative Medicine and Cell Biology

Medical University of South Carolina • Charleston, SC

1d • Onsite

About The Position

The individual will be under supervision of the PI, will participate in routine experiments and the maintenance of a basic biomedical science laboratory, with emphasis on transgenic mouse colony establishment and maintenance, embryonic and adult mouse histology and immunohistochemistry, light microscope imaging, preparation of solutions and reagents, equipment sterilization, and basic cell/tissue culture. These duties will be utilized to assist in the identification of anti-liver cancer signaling factors during liver damage repair. The individual will also assist the PI to select and order reagents. Work is conducted in a basic biomedical laboratory that focuses on Liver diseases, regeneration and cancer.

Requirements

• A bachelor's degree in chemistry, biology, or other natural, life or health care science and one year work experience directly related to the assigned research area.
• Must be able to work with animals (mouse).
• Ability to perform job functions in an upright position.
• Ability to perform job functions in a seated position.
• Ability to perform job functions while walking/mobile.
• Ability to climb, using step stool.
• Ability to work in temperature extremes (32° F to 100° F) when required due to assignments in cold rooms and/or foreign countries.
• Ability to work in confined/cramped spaces.
• Ability to bend at the waist.
• Ability to twist at the waist.
• Ability to fully use both hands/arms.
• Ability to perform repetitive motions with hands/wrists/elbows and shoulders.
• Ability to fully use both legs.
• Ability to reach in all directions, stretch, bend, while moving items/materials from both sitting and standing positions.
• Ability to maintain good olfactory sensory function/distinction.
• Ability to lift materials up to 20 lbs., unassisted.
• Ability to lift and carry 4 liter waste material bottles a distance of 30 feet, unassisted.
• Ability to lift and carry 25-30 lbs. jugs of liquid a distance of 100 feet, unassisted.
• Ability to lift file boxes, from floor level to counter tops, unassisted.
• Ability to lift 40 lbs. centrifuge rotors from floor level to height of 40 inches, then down 20 inches into centrifuge drum, unassisted.
• Ability to lift 25 lbs. boxes, from floor level to maximum height of 72 inches, unassisted.
• Ability to push/pull file boxes from one location to another at floor level.
• Ability to maneuver heavy equipment on bench tops, 50 lbs. or greater, unassisted.
• Ability to perform gross motor functions with frequent fine motor movements.
• Ability to maintain 20/40 vision, corrected, in one eye or with both eyes.
• Ability to match or discriminate between colors, normally.
• Ability to hear and recognize various alarms emitting from work area systems.
• Ability to hear and/or understand conversations.
• Ability to work in a darkroom for processing film, etc.
• Ability to be qualified physically for respirator use, initially and annually.
• Ability to work rotating shifts as required.
• Ability to work overtime as required.
• Ability to learn and use new processes, tools and equipment as required.

Nice To Haves

• Bachelor’s degree in biology, chemistry, biochemistry, molecular biology or other life science is preferred.
• Strong organizational, record keeping, and interpersonal communication skills required.
• Experience of various laboratory techniques including animal husbandry, PCR and recombinant DNA work, western blotting, cell culture, histology and immunostaining, and microscopic imaging.
• Prior experience in lab management roles is preferred.

Responsibilities

• Designing and planning routine experiments, including optimization of daily experimental protocols, selection and ordering reagents and lab supplies.
• Maintaining an accurate and timely experimental records.
• Share responsibility for mouse husbandry, including transgenic mouse colony breeding, maintenance, and expansion.
• Histology and immunohistochemistry, including tissue collection, processing and embedding, sectioning, staining, and imaging.
• Basic molecular biology and biochemistry experiments: DNA isolation, genotyping, real-time PCR, western blotting.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level