UNIV - Research Specialist I - Pharmacology and Immunology

Medical University of South Carolina•Charleston, SC
•$37,944 - $60,690

About The Position

The Nozaki lab at the Medical University of South Carolina studies intestinal immunity during infection and inflammation, with particular focus on cell death and related pathways. The lab also investigates how intestinal inflammation affects tumor evolution and the tumor microenvironment, and how these mechanisms may inform therapeutics. Its research uses novel mouse and organoid models to examine cell-death signaling and cell-to-cell and host-pathogen interactions. Under the direct supervision of the Principal Investigator, the Research Specialist I supports immunology research involving mouse gut tissues and cells. The role includes mouse colony care and sample preparation, laboratory analyses, equipment and resource maintenance, and support for research documentation and protocols. Experience with the listed techniques is helpful but not required; the lab offers training opportunities.

Requirements

  • High school diploma and two years of work experience in a clinical or research setting, or a bachelor's degree in chemistry, biology, or another natural, life, or health care science in place of the two years of experience.
  • Ability to work rotating shifts and overtime as required.
  • Ability to learn and use new processes, tools, and equipment as required.
  • Ability to meet the physical requirements described in the posting, including frequent movement and handling or carrying laboratory materials and equipment, with some listed tasks requiring lifting up to 50 pounds or more.

Nice To Haves

  • Bachelor's degree in immunology, molecular biology, or cell biology.
  • Experience with the listed laboratory techniques; experience is a plus but not required.

Responsibilities

  • Prepare mouse tissues for analysis, including dissection and tissue harvesting, histopathology analysis, cell culture, molecular cloning, cell transfection or infection, quantitative real-time PCR, Western blotting, immunostaining, microscopy, and flow cytometry.
  • Maintain the mouse colony, including breeding and genotyping.
  • Maintain laboratory equipment using checklist systems, suitability checks, and required maintenance.
  • Assist with ordering reagents and laboratory supplies.
  • Help keep the laboratory safe, clean, and compliant by maintaining a neat workspace, wearing appropriate personal protective equipment, and labeling and inspecting laboratory items and solutions.
  • Maintain a detailed notebook of experiments and record where data are stored.
  • Assist with grant writing and IACUC protocols and amendments when appropriate.
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