Research Services Professional (Open Rank: Intermediate - Senior)

University of Colorado•Aurora, CO

5d•Onsite

About The Position

A Research Services Professional position is available in the laboratory of Francisco J. Asturias, in the Department of Biochemistry and Molecular Genetics at the University of Colorado Anschutz Medical Campus. The Asturias group works on structural (cryo-EM), biochemical and mechanistic studies of macromolecular complexes involved in various essential cellular processes. The person in this position will be focused on biochemical, molecular biology, genomic, and mechanistic characterization of the transcriptional Mediator complex, with emphasis on understanding the mechanism for Mediator’s role in enabling signal-induced transcription initiation. Extension of the work to participate in cryo-EM studies is also a possibility. Applicants with background in biochemistry, molecular biology, genomics, and experience in recombinant protein expression and purification would be particularly well qualified. The work will involve extensive interaction with other group members and the applicant will receive training and acquire expertise in all experimental approaches used in the Asturias lab. The position will report directly to Dr. Asturias. The person in this position must be highly motivated and well-organized, and capable of working both independently and as a member of a research team. They will be expected to interact and collaborate with other members of the Asturias lab and with collaborators at CU Anschutz and beyond. Good troubleshooting skills and ability to interpret, organize, and communicate experimental data are a must.

Requirements

Bachelor’s degree in biology, molecular biology, chemistry, genetics or related field
One (1) years professional level research experience (for Intermediate Professional)
Two (2) years professional level research experience (for Senior Professional)
Applicants must meet minimum qualifications at the time of hire.
Proficient knowledge of basic laboratory techniques including safety procedures and techniques
Ability to communicate effectively, both in writing and orally
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
Outstanding customer service skills
Knowledge of basic human anatomy, physiology medical terminology
Ability to interpret and master complex research protocol information
Applicants must be legally authorized to work in the United States without requiring sponsorship. We are unable to provide work visa sponsorship and employment authorization for this position now or in the future.

Nice To Haves

Laboratory experience with techniques specifically used in the Asturias lab, as outlined in the job summary section
Background in biochemistry, molecular biology, genomics, and experience in recombinant protein expression and purification
Extension of the work to participate in cryo-EM studies is also a possibility.

Responsibilities

Conduct biochemical and structural studies of Mediator. This might include work on bacterial, insect, and mammalian cell culture, protein expression/purification, CRISPR/Cas9 experiments, biochemical studies, genomic studies (e.g., RNA-Seq, Chip-Seq, CUT&RUN)
Summarize, interpret and communicate experimental results
Presentation of research at group and local meetings
Maintaining relationships with collaborators, including coordination of experimental work