Research Senior Technician - Pathology

The Ohio State University

2d • Onsite

About The Position

The laboratory of Dr. Latha P. Ganesan at The Ohio State University is hiring a Research Technician/Lab Manager to support an immunology research program focused on the cellular and molecular mechanisms of disease pathogenesis. This role offers the opportunity to work at the forefront of applied immunopathology research with direct relevance to human disease. The position provides hands-on experience with mouse models, including surgical procedures, transgenic and cell type–specific knockout systems, single-cell preparation from organs, and primary mouse and mammalian cell culture. It involves advanced immunological and molecular techniques, including Western blotting, immunofluorescence, immunohistochemistry, ELISA, immunoprecipitation, flow cytometry, CRISPR-based genome editing, transfection, and molecular biology approaches such as cloning and plasmid preparation. The candidate will also gain experience in studying liver clearance function, including assessment of hepatic clearance pathways in disease models, as well as conducting protein–protein interaction studies and measuring binding affinities using Biacore (surface plasmon resonance)–based assays. The candidate will play a central role in executing and optimizing experiments in a dynamic, hypothesis-driven research environment. Additional responsibilities include data organization and analysis, reagent and sample management, supervision and training of undergraduate students, and coordination of shared equipment and laboratory workflows. The position also includes maintaining IACUC, IBC, and biological and chemical safety compliance, supporting lab inspections, and contributing to general lab operations, including ordering and inventory management.

Requirements

• Bachelor's Degree or equivalent experience required.
• 4 years of relevant experience required with High School diploma or GED.
• 2 years of relevant experience required with Associate's Degree.
• 0 years of relevant experience required with Bachelor's Degree.
• Strong hands-on experience in mouse models, including surgical procedures.
• Highly organized, detail-oriented, and able to work both independently and collaboratively.
• Able to manage multiple projects in a fast-paced research environment.

Nice To Haves

• Master's degree in biology or a related field.
• Experience with transgenic or conditional knockout models is strongly preferred.

Responsibilities

• Executing and optimizing experiments in a dynamic, hypothesis-driven research environment.
• Data organization and analysis.
• Reagent and sample management.
• Supervision and training of undergraduate students.
• Coordination of shared equipment and laboratory workflows.
• Maintaining IACUC, IBC, and biological and chemical safety compliance.
• Supporting lab inspections.
• Contributing to general lab operations, including ordering and inventory management.

Benefits

• Medical, dental and vision coverage, with Ohio State paying a significant portion of the cost.
• Paid time off, including sick and vacation time and 11 holidays.
• State retirement plan or an alternative retirement plan, both with generous employer contributions.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level