Research Scientist

University of Colorado•Aurora, CO

42d•$72,000 - $80,000•Onsite

About The Position

Our laboratory develops translational models of transplantation and regeneration to study immune responses, neuronal connectivity, and tissue integration in experimental models of tissue transplantation and nerve repair. Current research efforts include the development of experimental models of whole eye transplantation and optic nerve injury to investigate mechanisms of immune rejection, regeneration, and functional recovery. The Research Scientist will lead and coordinate experimental studies integrating transplant immunology, molecular biology, and surgical animal models. Responsibilities include contributing to experimental design, supervising in vivo and molecular studies, mentoring trainees, and participating in scientific publications and research proposals within a collaborative multidisciplinary research environment. This project offers the opportunity to contribute to a unique experimental model at the intersection of neuroscience, transplantation, and vision restoration.

Requirements

PhD in Immunology, Molecular Biology, Cell Biology, or a related biomedical discipline.
Minimum 3-5 years of postdoctoral research experience in transplant immunology, immune rejection mechanisms, or related areas.
Demonstrated research experience investigating immune responses in transplantation or related experimental models.
Strong publication record with at least 10 peer-reviewed manuscripts with first-author or co-author contributions.
Experience working with in vivo experimental models, including large animals.

Nice To Haves

Research experience in transplant immunology.
Experience studying immune tolerance mechanisms in transplantation models.
Training in cellular and molecular mechanisms of immune regulation.
Experience mentoring or supervising students or research trainees.
Strong collaborative and organizational skills in multidisciplinary research environments.
Experience working with large animal models, including swine transplantation or surgical research models.
Experience in optic nerve injury, transection, or regeneration models.
Expertise in immunological and molecular techniques including flow cytometry, ELISA, immunohistochemistry, immunocytochemistry, and immunofluorescence.
Experience supporting or collaborating in surgical experimental models.
Familiarity with Good Scientific Practices (GSP), Good Cell Culture Practices (GCCP), and regulatory compliance in animal research.

Responsibilities

Lead and coordinate experimental research studies investigating immune responses, rejection mechanisms, and regenerative processes in transplantation and optic nerve injury models.
Design and implement in vivo studies using small and large animal models, including rodent and swine systems.
Oversee and conduct molecular and cellular analyses including flow cytometry, ELISA, immunohistochemistry, immunofluorescence, and related cell-based assays.
Analyze and interpret experimental data and contribute to preparation of scientific manuscripts, reports, and conference presentations.
Contribute to the development of research proposals and grant applications supporting laboratory research programs.
Recruit, mentor, and train undergraduate, graduate, and postdoctoral trainees in experimental design and laboratory techniques.
Coordinate experimental activities with veterinary staff and research collaborators to ensure compliance with institutional and regulatory standards.