Research Scientist, Lentiviral Vector Purification and Analytics

Novartis • Cambridge, MA

3d • $66,800 - $150,800 • Onsite

About The Position

The Lentiviral Vector (LVV) Team in the Biologics Research Center (BRC) at Novartis, Cambridge, MA is seeking a highly motivated Research Scientist with experience in production and purification of viral vectors to join our team. In this role, you will play a key part in advancing our Cell and Gene Therapy research initiatives and contributing to groundbreaking research in CAR-T cell therapy. This role is based in Cambridge, MA/USA. Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you. Join a collaborative team at the forefront of cell and gene therapy research. As a Research Scientist focused on lentiviral vector purification and analytics, you will apply hands-on laboratory expertise to help develop, optimize, and characterize viral vector processes that support next-generation CAR-T programs. This role offers the opportunity to contribute directly to innovative science, work across purification and analytical workflows, and help advance high-quality research materials that enable transformative therapeutic approaches.

Requirements

• BS or MS in bioengineering, virology, or related field, with relevant lab experience.
• 1–3 years of experience in protein and/or viral vector purification.
• Hands-on experience with chromatography and filtration techniques, including TFF and depth filtration.
• Strong coordination, communication, collaboration, learning agility, and self-motivation.
• Proficiency with Word, Excel, PowerPoint, and GraphPad Prism.
• Excellent oral, written, and interpersonal communication skills.

Nice To Haves

• BSL2 experience with AAV, lentiviral, or retroviral vector production.
• Proficiency in aseptic technique, cell culture, molecular biology, and analytical testing.
• Bioreactor experience.

Responsibilities

• Execute hands-on laboratory activities related to lentiviral vector purification including clarification, chromatography and TFF.
• Execute analytical methods (molecular- and cell-based) to assess quality of the purified vector.
• Write and review protocols, technical reports, and technology transfer documents with supported conclusions and recommendations.
• Write and review SOPs, instrument procedures, and other lab documents.
• Plan and prioritize work to meet goals while managing multiple research activities.
• Support experimental design, data analysis, and troubleshooting.
• Identify root causes, implement solutions, and verify effectiveness.
• Present scientific data and contribute openly to discussions.
• Document experimental procedures and processes thoroughly.
• Collaborate across teams, share knowledge, and train team members in technical areas as needed.

Benefits

• Health, life and disability benefits
• 401(k) with company contribution and match
• Generous time off package including vacation, personal days, holidays and other leaves

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Associate degree