Research Scientist II -Sarthy Lab

Seattle Children's Hospital•Seattle, WA

2d•Onsite

About The Position

The Sarthy Lab at Seattle Children's Research Institute (Ben Towne Center) studies cancer epigenetics, with a focus on how chemotherapies and epigenetic agents act on chromatin and transcription in pediatric cancers. We are looking for a Research Scientist to join a collaborative team working at the intersection of chromatin biology, genomics, and pediatric oncology.

Requirements

Bachelor’s Degree in an engineering or scientific discipline; may require a Master’s Degree for certain lab specialties.
Minimum of two (2) years’ experience in a related area/laboratory setting.

Nice To Haves

Master's Degree or Ph.D. in molecular biology, biochemistry, genetics, or a related field.
Hands-on experience with mammalian cell culture and molecular biology techniques.
Experience with chromatin profiling, CRISPR editing, or NGS library preparation is a plus.
Experience with laboratory management, including ordering, inventory, and maintaining protocols.
Comfort with basic data analysis (R, Python, or command line) is a plus.
Interest in cancer biology and translational research.

Responsibilities

Independently selecting and applying molecular and cell biology techniques, including mammalian cell culture, CRISPR/Cas9 genome editing, chromatin profiling (CUT&Tag, CUT&RUN), sequencing library preparation, and flow cytometry.
Contributing to experimental planning, design, execution and interpretation.
Keeping detailed records.
Helping prepare figures, manuscripts, presentations and grant proposals.
Presenting at lab meetings.
Helping train and mentor junior lab members.
Working with our automated CUT&Tag platform and with collaborators across SCRI, Fred Hutch and UW.