Research Scientist II, Biochemistry

Novartis • Cambridge, MA

2d • $81,200 - $150,800 • Onsite

About The Position

This onsite, laboratory-based in vitro Research Scientist position is part of the Cardiovascular and Metabolic Disease (CVM) Biochemistry unit at Novartis Biomedical Research in Cambridge, Massachusetts. The scientist will contribute to target validation, assay development, and drug profiling for exploratory and pipeline projects, working with therapeutic molecules including small molecules and biologics. The role involves collaboration with colleagues across the broader research organization to advance research projects and help develop medicines for cardiovascular and metabolic diseases.

Requirements

• Bachelor's or Master's degree in biology, biochemistry, cell biology, or a related life science field; at least a Bachelor's degree is required.
• At least 4 years of relevant post-graduate research experience.
• Strong attention to detail and ability to quickly learn new techniques.
• Knowledge of statistics and computational data analysis.
• Strong communication and creative problem-solving skills.
• Ability to work collaboratively in a matrixed team environment.
• Exemplary laboratory practices and record-keeping skills.
• Flexibility, aptitude for learning, and a passion for driving groundbreaking science.

Nice To Haves

• Experience culturing, differentiating, and genetically engineering human induced pluripotent stem cell-derived cardiomyocytes via viral transduction.
• Research experience in cardiovascular or metabolic disease, such as heart failure, obesity, atrial fibrillation, or atherosclerosis.

Responsibilities

• Plan and execute biochemical and cell-based assays to support drug discovery.
• Perform in vitro experiments for assay development, therapeutic lead profiling, target validation, and mechanism-of-action studies.
• Use laboratory techniques including cell culture, quantitative polymerase chain reaction, gene knockdown with small interfering RNA, immunofluorescence microscopy, and Western blotting.
• Analyze data and accurately document experiments in the electronic laboratory notebook.
• Present results at laboratory and department meetings.
• Assist in writing research documents and scientific publications.

Benefits

• Performance-based cash incentive.
• Depending on role level, eligibility to be considered for annual equity awards.
• Health benefits.
• Life benefits.
• Disability benefits.
• 401(k) with company contribution and match.
• Vacation, personal days, holidays, and other leaves.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level