Research Scientist I - Vascular Biology Laboratory

University of North Texas System • Denton, TX

1d • Onsite

About The Position

The Vascular Biology Laboratory in the Department of Biological Sciences at the University of North Texas seeks a long-term staff Research Scientist to support the daily operation of a growing research laboratory. The position coordinates experimental work, conducts mouse and cell-based studies, maintains continuity across projects, troubleshoots routine issues, and guides student researchers. The laboratory studies endothelial function in metabolic disease, thrombosis, and stroke. This is a full-time staff research role combining bench work with practical laboratory organization and coordination.

The Research Scientist will coordinate schedules and workflows across projects; carry out mouse handling, cell culture, and molecular and cellular assays; maintain records, samples, inventory, and equipment needs; and analyze and communicate results. The scientist will also assist with training undergraduate and graduate researchers and organizing data and methods for reports, presentations, and publications. Specialized endothelial methods will be learned in the laboratory. Mouse procedures are performed after appropriate training and protocol authorization.

Requirements

• Master’s degree in biology, biochemistry, molecular or cell biology, or a closely related field.
• At least three years of hands-on laboratory research experience, including organizing experiments and working independently with established protocols.
• Prior hands-on mouse experience, including restraint, genotyping, injections, and at least one routine identification or tissue-sampling procedure, such as ear tagging or tail sampling.
• Working familiarity with aseptic cell culture technique and routine mammalian cell culture maintenance, including preparation of a sterile workspace, feeding, and passaging cultured cells.
• Experience with basic molecular biology methods, including PCR, immunoblotting, ELISA, immunofluorescence microscopy, and flow cytometry.
• Accurate record keeping and communication of experimental results.
• Applicants must submit at least two professional references as part of the application; additional references may be added after submission.

Nice To Haves

• Experience coordinating work across multiple projects or providing day-to-day guidance to students or junior lab members.
• Ability to work independently while thriving in a collaborative team setting and leading multiple projects concurrently.
• Experience with genetically engineered mouse colonies and/or phenotyping.
• Experience with human primary cell culture, particularly endothelial cells.
• Research experience in vascular biology, metabolism, thrombosis, or a related area.

Responsibilities

• Coordinate day-to-day experimental schedules and workflows across projects, track samples, and follow planned studies through to completion in collaboration with the principal investigator.
• Perform routine mouse handling, restraint, identification, and sample collection; assist with mouse colony records, genotyping, experimental procedures, and tissue collection after appropriate training and protocol authorization.
• Maintain cell cultures using aseptic technique and perform molecular and cellular assays, which may include PCR, immunoblotting, ELISA, immunofluorescence microscopy, and flow cytometry; learn the laboratory’s specialized endothelial methods.
• Maintain accurate experimental records, analyze and present data, manage inventory and equipment needs, and identify operational problems early so they can be resolved promptly.
• Assist Dr. Sacharidou in training and guiding undergraduate and graduate researchers in established procedures, safe practices, and rigorous record keeping.
• Organize data and methods for reports, presentations, and publications as needed.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level