Research Scientist I - Vascular Biology Laboratory

University of North Texas System • Denton, TX

3d • Onsite

About The Position

Dr. Anastasia Sacharidou's Vascular Biology Laboratory seeks a long-term staff Research Scientist to serve as a key partner in the daily operation of a growing research lab. The scientist will coordinate experimental work, conduct mouse and cell-based studies, maintain continuity across projects, troubleshoot routine problems, and guide student researchers. The laboratory studies endothelial function in metabolic disease, thrombosis, and stroke. This is a full-time staff research position combining bench work with the practical work of keeping a laboratory organized and moving forward.

The position is in the Department of Biological Sciences at the University of North Texas in Denton. The work schedule varies based upon assignment. Compensation is competitive and commensurate with the candidate’s qualifications, experience, and discipline, in accordance with university guidelines and available funding.

Requirements

• Master’s degree in biology, biochemistry, molecular or cell biology, or a closely related field.
• At least three years of hands-on laboratory research experience, including organizing experiments and working independently with established protocols.
• Prior hands-on experience with mice, including restraint, genotyping, injections, and at least one routine identification or tissue-sampling procedure, such as ear tagging or tail sampling.
• Working familiarity with aseptic cell culture technique and routine mammalian cell culture maintenance, including preparation of a sterile workspace, feeding, and passaging cultured cells.
• Experience with basic molecular biology methods, including PCR, immunoblotting, ELISA, immunofluorescence microscopy, and flow cytometry; accurate record keeping; and communication of experimental results.
• Applicants must submit a minimum of two professional references as part of their application.

Nice To Haves

• Experience coordinating work across multiple projects or providing day-to-day guidance to students or junior lab members.
• Experience working independently while thriving in a collaborative team setting, and leading multiple projects concurrently.
• Experience with genetically engineered mouse colonies and/or phenotyping.
• Experience with human primary cell culture, particularly endothelial cells.
• Research experience in vascular biology, metabolism, thrombosis, or a related area.

Responsibilities

• Coordinate day-to-day experimental schedules and workflows across projects; track samples and follow planned studies through to completion in collaboration with the principal investigator.
• Perform routine mouse handling, restraint, identification, and sample collection; assist with mouse colony records, genotyping, experimental procedures, and tissue collection after appropriate training and protocol authorization.
• Maintain cell cultures using aseptic technique and perform molecular and cellular assays, which may include PCR, immunoblotting, ELISA, immunofluorescence microscopy, and flow cytometry; learn the laboratory’s specialized endothelial methods.
• Maintain accurate experimental records, analyze and present data, manage inventory and equipment needs, and identify operational problems early so they can be resolved promptly.
• Assist Dr. Sacharidou in training and guiding undergraduate and graduate researchers in established procedures, safe practices, and rigorous record keeping; organize data and methods for reports, presentations, and publications as needed.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level