Research Scientist 3, Genomics - Department of Genome Sciences

University of Washington•Seattle, WA

8d•Onsite

About The Position

The Department of Genome Sciences’ Northwest Genomics Center (NWGC) (Wei Lab) has an outstanding opportunity for a Research Scientist 3, Genomics, to join the team. Reporting to the NWGC Director of Operations, the Research Scientist 3 will conduct laboratory research focusing on the identification of DNA variation in human populations in a high-throughput genomics laboratory in the Department of Genome Sciences. This position will require expertise in molecular biology and genomics protocols and the ability to perform research and take responsibility for assuring quality, cost effectiveness and timeliness for large projects. The Research Scientist will work within the NWGC supporting production-scale genomics, while also supporting advanced research projects as part of the Wei lab. The Research Scientist 3 will work under supervision of the PI and Lead Research Scientist to meet project deadlines and complete assigned tasks by implementing well-established protocols and evaluating and developing new protocols. Weekly meetings are held to discuss project status. This position will work in a prominent laboratory whose work impacts other researchers worldwide. High functionality will be reflected in even greater funding opportunities and enhancement of the reputation of the University as a biomedical research powerhouse.

Requirements

Bachelor’s degree in Biology, Genetics/Biochemistry, Chemical or Biomedical Engineering, or other related Life Sciences field.
Four or more years of laboratory experience to include: Working knowledge of molecular biology, genetics, and/or chemistry and excellent technical wet bench skills
Ability to perform cell culture of established lines and manipulate nucleic acid, tissues, nuclei and chromatin
Demonstrated experience in -omics library construction
Experience in performing a broad range of short-read and long-read sequencing analyses
Ability to provide both written and oral summary of technical implementation, evaluation and recommendation of early-stage technologies.
Experience working with sequencing technologies, such as Illumina, PacBio and Oxford Nanopore
Experience growing human cell lines

Nice To Haves

Experience in a high-throughput genomics laboratory specializing in next-generation sequencing
Experience with liquid handling systems, specifically, Janus, Zephyr, and Sciclone systems, including program development
Experience working in a CLIA-certified environment
Excellent recording keeping and ability to refine and develop protocols
Proven analytical and problem-solving skills
Excellent written, verbal and interpersonal communication skills
Must be highly organized with solid attention to detail
Open to receiving direction and to asking for assistance when needed
Ability to work both independently and collaboratively

Responsibilities

Carry out laboratory protocols for next-generation DNA and RNA library construction and sequencing.
Perform standard and lab-developed molecular biology protocols.
Develop new methods for DNA, RNA, and methylation analysis.
Evaluate new products, kits, and instruments to assess their applicability and potential benefit to the Wei Lab and NWGC.
Maintain and harvest cell lines for a variety of molecular biology applications.
Develop and maintain precise laboratory protocols and records.
Work within a laboratory team environment to process and track DNA and RNA samples.
Program and operate robotics stations for sample preparation.
Implement quality-assurance protocols.
Works with laboratory information systems (LIMS) to log workflow data.
Perform assessments of data quality.
Assist with trouble-shooting and daily quality control of data.
Aid in the development of new experimental methods and assist laboratory co-workers and/or the PI in meeting long-term scientific goals.
Attend Genome Sciences and University meetings, retreats, status updates, orientations and planning days when necessary.
Other duties as assigned