Research Laboratory Manager NEUROLOGY kl

Mass General Brigham•Boston, MA
•Onsite

About The Position

The Khurana Lab seeks a highly organized, hands-on Laboratory Manager to lead the day-to-day operations of a large, collaborative research laboratory. The role focuses on proactively managing shared resources, equipment, supplies, workflows, documentation, and team coordination so research projects can proceed efficiently. The manager will also contribute directly to scientific projects as an experienced technician who continues developing technical expertise while growing as an operational leader. The position supports the Department's research faculty and programs through research and research-administration activities. It manages laboratory personnel and the overall functioning of the research operation, and serves as a resource for departmental researchers and a liaison to internal administrative units and external sponsors regarding research programs. The role requires regular on-site presence in a biomedical research laboratory and office environment.

Requirements

  • Bachelor's degree (BA/BS) in biology, neuroscience, molecular/cellular biology, bioengineering, or a related scientific field; experience may be accepted in lieu of a degree.
  • Three to five or more years of progressively responsible research experience in an academic, biotechnology, or biomedical research laboratory; experience in an academic or laboratory research setting is required.
  • Demonstrated experience with laboratory organization, operations, or management, preferably in a medium-to-large collaborative research group.
  • Strong hands-on technical background.
  • Strong technical foundation in molecular biology, biochemistry, and mammalian tissue culture.
  • Exceptional organizational skills, attention to detail, reliability, and follow-through across multiple people, projects, resources, and deadlines.
  • Strong communication and interpersonal skills, including the ability to coordinate effectively across a large collaborative team.
  • Proactive, solutions-oriented approach; ability to identify problems early, troubleshoot effectively, prioritize competing needs, and drive issues to resolution.
  • Ability to balance operational leadership with hands-on scientific work and shift priorities when laboratory or project needs require it.
  • Demonstrated independence, initiative, sound judgment, and ownership of responsibilities.
  • High degree of computer literacy and comfort with digital systems for laboratory operations, inventory, scheduling, documentation, and data organization.
  • Ability to make independent decisions and effectively supervise others.
  • Aptitude for technical problem solving, excellent organizational skills, strong budget and management skills, and the judgment to interpret information.

Nice To Haves

  • An advanced degree.
  • Human pluripotent stem cell culture experience.
  • Experience with genome editing, microscopy/high-content imaging, and molecular or biochemical assays.
  • Experience training, mentoring, or coordinating junior research staff, students, or trainees.

Responsibilities

  • Lead and coordinate day-to-day laboratory operations, serving as a central point of contact for shared laboratory needs and working with the PI, senior scientists, research staff, students, and collaborators.
  • Oversee shared spaces, equipment, supplies, reagents, consumables, common stocks, and laboratory repositories.
  • Manage inventory and ordering, anticipate laboratory needs, track critical supplies, coordinate purchasing, and address operational issues before they disrupt research.
  • Oversee shared equipment readiness, routine maintenance, service coordination, scheduling, documentation, and troubleshooting or escalation of equipment issues.
  • Maintain and improve operational systems, including shared logs, SOPs, quality assurance practices, resource tracking, laboratory documentation, and workflows that promote reproducibility and accountability.
  • Coordinate resources and workflows for research projects, help troubleshoot logistical and technical barriers, and ensure teams have the materials, equipment, and operational support needed to meet project goals and timelines.
  • Orient and train new staff, students, and visiting researchers on laboratory workflows, shared resources, technical practices, and operational expectations; help coordinate onboarding and offboarding.
  • Communicate across the collaborative team, reinforce shared laboratory practices, follow through on action items, and translate operational decisions into clear workflows and responsibilities.
  • Identify inefficiencies and implement solutions that improve organization, communication, safety, compliance, resource stewardship, and laboratory throughput.
  • Perform specialized experimental procedures and contribute to research projects, particularly in stem cell culture and differentiation, molecular biology, genome editing, microscopy, and related cellular assays.
  • Participate in the design, optimization, documentation, and troubleshooting of experimental protocols and research workflows.
  • Provide hands-on technical guidance and training to research assistants, students, and laboratory members; promote rigorous experimental documentation, quality control, and reproducibility.
  • Analyze and communicate experimental results and contribute to reports, presentations, manuscripts, and other scientific materials as appropriate.
  • Maintain and expand technical expertise, and help evaluate and implement technologies, methods, and workflows that strengthen laboratory research capabilities.
  • Supervise laboratory operations and oversee laboratory funds, supply inventory, and staff activities.
  • Coordinate regulatory and compliance activities and serve as the laboratory safety officer.
  • Contribute to scientific literature and may present data at meetings.
  • Perform other duties as assigned.

Benefits

  • Competitive base pay.
  • Comprehensive benefits.
  • Career advancement opportunities.
  • Differentials, premiums, and bonuses as applicable.
  • Recognition programs designed to celebrate contributions and support professional growth.
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