Research Lab Technician II - Data Analysis

University of Southern California • Los Angeles, CA

8h

About The Position

The USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, Titus Family Department of Clinical Pharmacy, is seeking a Research Lab Technician II to support studies in immunogenomics, cancer genomics, and therapeutics. The translational genomics and experimental therapeutics lab investigates novel therapeutic targets in acute myeloid leukemia (AML) and develops therapeutic strategies. The role supports data analysis as well as laboratory operations and research activities.

Requirements

• Bachelor’s degree in biology, molecular biology, biochemistry, immunology, or a related field; the posting also lists minimum education as an associate’s degree, specialized/technical training, or combined experience and education as a substitute.
• Minimum two years of experience.
• Working knowledge of laboratory equipment and research protocols.
• Knowledge of computer analysis techniques and ability to provide routine analysis and interpretation of research data.
• Hands-on laboratory experience with routine molecular biology and cell culture techniques.
• Excellent organizational, record-keeping, and communication skills.
• Ability to work independently and as part of a team.

Nice To Haves

• Master’s degree or 1–2 years of research laboratory experience.
• Experience with flow cytometry, NGS sample preparation, or high-throughput assays.
• Experience with mouse handling and in vivo studies.
• Familiarity with basic data analysis tools such as R, Python, or GraphPad Prism, or interest in learning bioinformatics.
• Background in cancer biology or hematologic malignancies.

Responsibilities

• Process next-generation sequencing data and perform quality control using established pipelines, including for RNA-seq, whole-exome/genome sequencing, ATAC-seq, ChIP-seq, and single-cell sequencing.
• Perform downstream analyses, including differential expression, variant calling and annotation, pathway enrichment, and clustering, under the guidance of the Principal Investigator and senior lab members.
• Analyze data from high-throughput drug screens, flow cytometry, and preclinical mouse studies, and perform basic statistical analyses.
• Mine public ‘omics’ resources, such as TCGA, BeatAML, GEO, and DepMap, to support target discovery and validation.
• Maintain, document, and update analysis pipelines and scripts using version control.
• Organize and manage laboratory datasets, sample metadata, and clinical annotations in compliance with IRB and data security requirements.
• Run jobs on USC’s high-performance computing cluster and manage data storage.
• Prepare figures, tables, and summaries of results for lab meetings, presentations, and manuscripts.
• Perform molecular, cellular, and in vivo experiments and support day-to-day laboratory operations.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Associate degree