A Research Instructor position in the Department of Pharmacology and Chemical Biology at the University of Pittsburgh is immediately available in the laboratory of Dr. Orlando Schärer. This is an Appointment Stream position. Research is focused on the interplay of DNA repair pathways and anticancer therapies. The aim is to investigate the mechanisms of action of the antitumor agents trabectedin and lurbinectedin in sarcoma, small cell lung cancer and additional cancer types with dysregulated transcription. The project involves biochemical, cell biological and genomic studies of the mechanism of how anticancer agents target specific tumor types. The long-term goal is to leverage mechanistic insights to improve anticancer therapies.
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Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree