Research Associate-Pharmaceutical Sciences

University of Tennessee•Memphis, TN

About The Position

Under the direction of an assigned supervisor, the Research Associate contributes to small-molecule drug development, supporting preclinical drug development in animal models. The role focuses on pharmacokinetic assessments, pharmacokinetic/pharmacodynamic modeling and simulation, pharmacometrics, and bioanalytical analysis using liquid chromatography–tandem mass spectrometry (LC-MS/MS). The position also supports laboratory operations, compliance, research documentation, and the training and mentoring of graduate assistants, junior fellows, research assistants, graduate students, and junior postdoctoral scholars. This is a grant-funded position funded through June 30, 2029.

Requirements

  • Ph.D. in pharmacology, pharmaceutical sciences, or a related field; transcript required.
  • Five years of experience in pharmacokinetic research and LC-MS-based analysis of small-molecule drugs and metabolites in biological fluids.
  • At least three years of experience as a Postdoctoral Scholar.
  • Experience maintaining and organizing laboratory space.
  • Ability to independently plan, develop, standardize, validate, and document LC-MS/MS-based assays, including sample preparation for drug quantitation in biological samples.
  • Demonstrated knowledge of handling and using pharmacokinetic animal models.
  • Knowledge and proficiency in population pharmacokinetic analysis techniques.
  • Ability to communicate effectively with colleagues from other disciplines and work as a motivated, creative, results- and milestone-oriented self-starter.
  • High competency and experience in pharmacokinetic data analysis.
  • Excellent oral, written, and presentation skills in English.

Nice To Haves

  • Experience in anti-infective drug development.
  • At least five years of experience in animal-based pharmacology research.
  • Knowledge and proficiency in clinical pharmacology and clinical research.

Responsibilities

  • Work independently and collaboratively with research laboratory members to oversee and perform research and contribute scientific expertise to experimental planning.
  • Plan, execute, document, and analyze in vitro and in vivo pharmacokinetic and drug metabolism studies.
  • Perform pharmacokinetic analyses and modeling using software including Phoenix WinNonlin, NONMEM, and R.
  • Develop and validate LC-MS/MS assays and analyze biological samples.
  • Assist with day-to-day activities for the assigned laboratory space.
  • Manage basic laboratory materials and equipment, including ordering and stocking supplies.
  • Assist in mentoring and training graduate assistants, junior fellows, research assistants, graduate students, and junior postdoctoral scholars in laboratory procedures and pharmacokinetic and bioanalytical techniques.
  • Assist with obtaining approvals and complying with requirements for experiments.
  • Present research data at scientific meetings and conferences.
  • Create and maintain thorough documentation of research activities and results, as well as laboratory safety policies, updating them as needed.
  • Perform other related duties as assigned.
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