Research Associate, Molecular Biology

Colossal Biosciences•Dallas, TX

6h•Onsite

About The Position

An affiliate of Colossal is seeking a motivated and detail-oriented Research Associate to join our interdisciplinary team at the intersection of molecular and developmental biology. This role offers the opportunity to work closely with scientists developing cutting-edge approaches to drive novel applications in the modification of phenotypes in avians. The successful candidate will support ongoing research projects by performing a range of cellular and tissue-based assays, including in situ hybridization, flow cytometry, histology, and immunofluorescence staining. This role is based in Dallas, TX. Relocation assistance is available.

Requirements

Bachelor’s degree (B.S./B.A.) in molecular biology, or a related life science field with 1 or more years of hands-on research experience in industry or academic research labs.
Hands-on experience in molecular cloning, plasmid construction, and plasmid preparation (mini-, midi-, and maxi-prep).
Demonstrated hands-on experience with at least two of the following: microscopy (confocal and/or lightsheet), in situ hybridization, flow cytometry, histology, immunofluorescence staining, (experience with all four strongly preferred)
Skilled in PCR primer design and PCR optimization/troubleshooting.
Strong organizational skills with the ability to manage multiple projects simultaneously and meet deadlines.
Excellent written and oral communication skills, with demonstrated problem-solving abilities.

Nice To Haves

Experience handling vertebrate embryos.
Familiarity with microscopy/imaging software (e.g., Imaris, ImageJ or similar)
Experience with transfection reagents (i.e. lipofectamine or electroporation)
Familiarity with high-throughput automation platforms for molecular biology workflows.

Responsibilities

Collaborate with developmental biologists to analyze gene expression and function across different developmental stages.
Perform in situ hybridization (ISH) to localize and quantify RNA/DNA targets in tissue and whole embryo samples
Prepare and process tissue samples for histology, including sectioning, fixation, and staining (H&E and special stains)
Perform immunofluorescence (IF) staining and support imaging/microscopy workflows
Conduct flow cytometry experiments, including sample preparation, staining panel setup, data acquisition, and basic analysis
Screen constructs in developing avian embryos to quantify expression patterns.
Produce transfection reagents to aid experimental workflows.
Analyze and interpret experimental data, providing recommendations to guide project direction.
Participate in meetings, generate reports, and present findings to ensure alignment with project milestones.
Maintain accurate, detailed laboratory records and demonstrate strong organizational skills.