Research Associate - III

LeadStack Inc. • Foster City, CA

3d • Onsite

About The Position

We are seeking a highly motivated, interactive, and creative individual to support drug discovery and development within Research. The successful candidate will be part of the Pathobiology Group which provides laboratory support throughout He/she will work closely with internal research groups as well as external collaborators to identify and validate novel drug targets in the areas of oncology, fibrosis, virology, and inflammation. Tissue-based endpoints will be used to investigate the efficacy and method of action and potential therapeutic targets. The successful candidate must be self-motivated and detail-oriented, exhibit excellent organizational and communication skills, demonstrate the ability to manage multiple priorities and work under tight timelines, thrive with a high degree of responsibility, and a proficient team-player. Specific duties will include optimization and/or validation of antibody reagents for IHC and CISH. He/she will have extensive experience in IHC, including method development, and will help with identification and implementation of process improvements in IHC and other histological techniques. He/she will work closely with internal research groups as well as external collaborators to identify and validate novel drug targets in the areas of oncology, fibrosis, virology, and inflammation. He/she will be responsible for development of tissue-based assays and will have a background in biology or a related discipline and laboratory experience in human and animal tissue preparation and image scanning. Experience with multiplex IHC assays is a plus, but not necessary. Development of infrastructure, tissue collections, technology and novel methodology will be implemented as needed through a combination of in-house efforts and the use of relevant CROs or other external expertise. The successful candidate must be able to independently plan, execute, and troubleshoot decisional experiments that support the initiation and/or advancement of drug candidate projects. The candidate will work cross-functionally within the organization to achieve goals, present research findings and recommendations to senior staff, and identify new technologies that may increase throughput or enhance our understanding of disease mechanisms.

Requirements

• Extensive experience in IHC, including method development.
• Background in biology or a related discipline.
• Laboratory experience in human and animal tissue preparation and image scanning.
• Ability to independently plan, execute, and troubleshoot decisional experiments.
• Proficiency with Microsoft Office is required.
• Ability to troubleshoot independently.
• Ability to use both strategic and tactical thinking effectively.
• Ability to show curiosity-driven engagement in scientific problems.
• Ability to manage more than one project at any given time.
• Ability to work successfully in a cross-functional and highly collaborative team environment.
• Ability to communicate clearly to a variety of audiences in both speech and writing.
• BS degree and 8+ years of relevant experience or an MS degree with 6+ years of experience.
• Work history should demonstrate direct participation in drug discovery and target identification/validation in oncology, fibrosis, inflammation, and virology research by IHC and other histological techniques.
• Necessary technical skills include IHC method-development protocols, tissue handling, and organized data entry.

Nice To Haves

• Experience with multiplex IHC assays is a plus, but not necessary.

Responsibilities

• Optimization and/or validation of antibody reagents for IHC and CISH.
• Identification and implementation of process improvements in IHC and other histological techniques.
• Development of tissue-based assays.
• Independently plan, execute, and troubleshoot decisional experiments that support the initiation and/or advancement of drug candidate projects.
• Work cross-functionally within the organization to achieve goals.
• Present research findings and recommendations to senior staff.
• Identify new technologies that may increase throughput or enhance our understanding of disease mechanisms.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior