Research Associate II, Translational Neuroscience (Galveston)

UTMB Health•Galveston, TX

22h

About The Position

The Research Associate II performs routine and non-routine research assignments and experiments of moderate complexity and assists with laboratory maintenance. Under general supervision, the role plans, coordinates, sets up, and conducts standard research experiments, prepares biological assays, performs quantitative and qualitative analyses, and may modify research procedures as directed by the Principal Investigator. The position maintains records of tests and collected data, provides preliminary analysis, and assists with compiling, tabulating, and analyzing final data. It also ensures laboratory equipment is accurately assembled, calibrated, operated, and modified according to applicable guidelines; maintains animal and environmental safety compliance and laboratory inventory; and performs literature searches as outlined by the Principal Investigator. The role may provide guidance to junior research staff and performs related duties as required. Preferred research expertise includes primary microglial cell culture and molecular assays, including nitrites, ELISA, and confocal microscopy; peptide bioelectrochemistry and electron transfer; cell-compatible TEER and wireless cyclic voltammetry; computational chemistry and single-photon spectroscopy; holotomography imaging; mitochondrial segmentation; live microglial and astrocyte cell analysis involving reactive nitrogen/oxygen species signaling; and engineering principles for multi-order differential equation mapping of amino acid chemistry damage. Spatial mapping, FLIR, FLIM, and knowledge of wireless devices for measuring radical and electrochemistry in cells are bonuses.

Requirements

Bachelor's degree in basic science or equivalent and 2 years of related experience, or a master's degree in basic science or equivalent with no experience required.
Skills in animal science/care and surgery.
Skills in biological assays, quantitative analysis, qualitative analysis, data analysis, and data tabulation.
Experience with equipment calibration, technical writing, and standard laboratory equipment.

Nice To Haves

Primary microglial cell culture experience with basic molecular assays, including nitrites, ELISA, and confocal microscopy.
Peptide bioelectrochemistry and electron-transfer experience using devices including cell-compatible TEER and wireless cyclic voltammetry.
Experience with computational chemistry and single-photon spectroscopy methods.
Understanding of wireless devices capable of measuring radical and electrochemistry in cells.
Experience with holotomography imaging, mitochondrial segmentation, and analysis of live microglial and astrocyte cells with reactive nitrogen/oxygen species signaling.
Experience with FLIR and FLIM.
Engineering principles in multi-order differential equation mapping of amino acid chemistry damage.
Experience with spatial mapping.

Responsibilities

Perform routine and non-routine research assignments and experiments of moderate complexity under general supervision.
Plan, coordinate, set up, and conduct standard research experiments following general technical instructions.
Prepare biological assays and conduct quantitative and qualitative analyses.
Modify research procedures as determined by the Principal Investigator.
Maintain records of tests performed and data collected, and provide preliminary analysis of results.
Assist with compiling and tabulating data and analyzing final data.
Ensure accurate assembly, calibration, operation, and modification of laboratory equipment in accordance with appropriate guidelines.
Maintain the laboratory for animal and environmental safety compliance.
Maintain laboratory inventory of supplies and equipment.
Perform literature searches as outlined by the Principal Investigator.
May provide guidance to junior research staff.
Adhere to internal controls established for the department.
Perform related duties as required.