Research Associate-II/Senior Research Associate, Histology (6-Month Contract)

SonoThera•South San Francisco, CA

2d•$42 - $48•Onsite

About The Position

The Bioanalytical group at SonoThera is seeking to hire an enthusiastic (Senior) Research Associate to support gene therapy drug development by performing histological procedures. We seek candidates who think critically and have the desire and ability to learn new techniques. This position requires adaptability and an ability to perform at a high level in a fast-paced environment. This is a 6-month contract position at 40 hours per week, with the possibility of extension or conversion to full-time employment. This position is 100% on-site and requires working from the office Monday through Friday. The role reports to the Sr. Director, Vivarium Operations & Bioanalytics.

Requirements

Advanced proficiency in FFPE tissue processing, embedding and sectioning and in mounting and cryosectioning of fresh frozen samples for a variety of tissues and species.
Experience performing routine stains such as H&E, PAS, and Masson’s Trichrome
Experience performing specialized stains such as IHC and ISH using autostainers such as Leica Bond RX, Ventana or similar.
Experience using imaging platforms such as VS200, 3dhistec P150/P250, Aperio Imagescope, Revolve or similar
Training or hands-on experience in sample management workflows.
Exceptional organizational skills including SOP documentation and record-keeping using ELN platforms such as Benchling.
Demonstrated commitment to laboratory safety and regulatory compliance.
Bachelor’s degree in biology, biomedical science, or a related field, with at least 2 years of relevant laboratory experience.
Strong communication, critical thinking, and problem-solving skills.

Nice To Haves

Experience preparing slides for DNA and RNA analysis (RNAscope, Visium, etc.) is a plus.
Optimizing antibodies for IHC/IF is a plus.
Experience using image analysis platforms such as HALO, Visiopharm or similar is a plus.
Industry experience preferred.

Responsibilities

Process, embed, and section FFPE and fresh frozen tissue samples.
Perform routine and specialized staining, including H&E, PAS, Trichrome, ISH, IHC, and IF.
Image stained slides and support qualitative and quantitative assessment of results.
Track sample accessioning, inventory, and chain of custody in the electronic lab notebook.
Document methods and results in SOPs and study records, and contribute to assay optimization.