Research Associate II, Product Development
About The Position
AskBio Inc., a subsidiary of Bayer AG, is a gene therapy company focused on developing life-saving medicines. The company has a portfolio of clinical programs targeting various diseases and utilizes proprietary technologies like Pro10™ for manufacturing. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, AskBio is dedicated to pioneering science to create transformative molecular medicines and improve patient lives. The Research Associate II is a technical role supporting platform, therapeutic pipelines, and R&D activities, with a primary focus on early cardiovascular programs. This role involves performing optimization, development, and data delivery with increased independence to support key preclinical studies in gene therapy R&D.
Requirements
- MS in Molecular Biology, Biochemistry or related field; or BS degree in Molecular Biology, Biochemistry or related field with 2+ years’ relevant laboratory experience; or High School Diploma with 6+ years’ relevant laboratory experience
- Hands-on experience with molecular biology techniques, including DNA/RNA isolation, SDS-PAGE, qPCR/ddPCR, and Western blot
- Prior experience with mammalian cell culture and aseptic technique
- Ability to follow established protocols with minimal supervision and deliver reliable, reproducible results
- Direct expertise with mammalian cell culture, including primary and immortalized cell systems, and strong aseptic technique
- Direct experience with quantitative molecular biology techniques, including isolation of DNA, RNA, and protein from cells and tissues; quantitative PCR and RT‑PCR (preference for direct experience with ddPCR); ELISA; SDS‑PAGE; and Western blot/automated Western (e.g., Jess)
- Strong data collection, documentation, and reporting skills, with the ability to work independently and as part of a research team
Nice To Haves
- Experience in NGS library production and sequencing is highly desired
- Comfort working across diverse experimental workflows and learning new techniques as project needs evolve
Responsibilities
- Support scientists in the design, planning, and execution of experiments to analyze protein, RNA, and DNA from in vitro and in vivo studies, contributing to key studies in gene therapy R&D
- Perform a broad range of experimental techniques independently (e.g., cell culture, nucleic acid and protein extraction, qPCR/RT-qPCR/ddPCR, ELISA, SDS-PAGE, Western blot/Jess, and related assays) to support platform and therapeutic programs
- Process, track, and analyze large numbers of samples in parallel while maintaining high quality and consistency in assay execution
- Maintain accurate, up to date records of all experimental work in electronic lab notebooks; support maintenance of databases, sample inventories, and reagent inventories as needed
- Assist in the development and optimization of experimental protocols; contribute to assay and workflow improvements
- Generate high quality, reproducible data and contribute to data analysis, interpretation, and presentation
- Contribute to and/or author study reports and study protocols
- Ensure laboratory areas are clean, safe, and well organized; monitor and restock common reagents and supplies; support proper operation and routine maintenance of equipment; and adhere to all safety and compliance guidelines
- Help coach and support peers within the workgroup (e.g., sharing best practices, cross training on internal assays) to enable effective day-to-day workflow
Benefits
- Equal Opportunity Employer
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
