Research Associate I, Pharmaceutical Development ~ Contract
About The Position
Nurix Therapeutics is a biopharmaceutical company focused on the discovery, development, and commercialization of small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. Leveraging Nurix’s extensive expertise in E3 ligases together with its proprietary DNA-encoded libraries, Nurix has built DELigase, an integrated discovery platform to identify and advance novel drug candidates targeting E3 ligases, a broad class of enzymes that can modulate proteins within the cell. Nurix’s drug discovery approach is to either harness or inhibit the natural function of E3 ligases within the ubiquitin proteasome system to selectively decrease or increase cellular protein levels. This role will provide scientific, technical, and hands-on support of drug discovery and product development related to small molecules from early discovery to clinical trial enabling studies.
Requirements
- Thorough understanding of basic chemistry principles
- Excellent basic quantitative laboratory skills including weighing, pipetting, and use of volumetric glassware
- Strong basic HPLC/UPLC skills and understanding
- Excellent organizational and documentation skills
- Proficiency in Microsoft 365
- Experience in safe handling of potent compounds
- BS/BA or higher in chemistry, pharmaceutics, engineering, or related field with 2 - 4 years of industry experience
Nice To Haves
- XRD and Mass Spec experience a plus
Responsibilities
- Prepare and characterize preclinical formulations in support of multiple programs.
- Perform stability and solubility testing using HPLC/UPLC.
- Assist with pre-formulation and formulation development for oral solid dosage forms.
- Contribute to internal and external presentations and publications.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
