Research Associate 2

Natera•San Carlos, CA

7d•$74,800 - $93,500•Onsite

About The Position

Join Natera’s R&D Scientific Operations as a Research Associate 2 on the Sample Processing team. You will execute Next-Generation Sequencing (NGS) workflows, cell-free DNA (cfDNA) extraction, and library preparation, generating the high-quality data required to advance our clinical diagnostic assays. Every sample represents a real person, and you will ensure accuracy, ethics, and compliance in sample management to directly impact patient care.

Requirements

BS/BA in a biological science or equivalent
Minimum of 2 years of related laboratory experience
Must pass a post-offer criminal background check
Extensive familiarity with good pipetting practices using single and multi-channel micropipettes and serological pipettes
Direct hands-on experience with library preparation and NGS platforms
Able to operate independently in the lab with strict attention to detail and precision
Proficiency with Laboratory Information Management Systems (LIMS) and database software
Proficiency with Microsoft Office (Word, Excel) and Google Drive
Clear, direct oral and written communication skills
Ability to think analytically, testing assumptions with data to troubleshoot and solve problems
Demonstrated strong interpersonal skills to build effective working relationships within the functional area
Manage competing priorities while operating with pace and precision in an evolving scientific environment

Nice To Haves

Experience with laboratory automation systems (e.g., Tecan, Hamilton, Beckman-Coulter) is strongly preferred

Responsibilities

Isolate plasma and buffy coat from whole blood and normalize plasma samples
Extract nucleic acids from whole blood or plasma using automated and manual extraction methods
Perform library preparation for Next-Generation Sequencing (NGS) using automated and manual methods
Determine the quantity and quality of nucleic acids using Quant-IT, Qubit, Nanodrop, BioAnalyzer, and qPCR
Load libraries onto NGS platforms, including NextSeq, MiSeq i100, NovaSeq, NovaSeq X Plus, and Revio
Interpret data to determine appropriate next steps based on rigorous outlined requirements
Perform routine laboratory equipment maintenance as defined in Standard Operating Procedures (SOPs)
Troubleshoot minor equipment malfunctions using data, escalating to the R&D equipment support team when necessary
Track sample inventory and status using Laboratory Information Management Systems (LIMS) and Google Sheets
Maintain precise records of lab work in LIMS, Google Sheets, Excel, and internal databases
Periodically review or draft SOPs and other work instructions
Take ownership of process improvements to increase operational precision and scale
Think team by partnering directly with R&D staff to define process needs and execute lab work without needing translation layers
Ensure accurate, ethical, and appropriate management of samples in compliance with all applicable federal regulations
Adapt to evolving science and operational needs, executing tasks that move the work forward
Handle protected health information (PHI) in paper and electronic formats as required to perform duties
Complete required HIPAA/PHI privacy and security training within the first 30 days of hire and maintain current status on all training